Nalpha-FMOC-L-Tryptophan

Nalpha-FMOC-L-Tryptophan Basic information

Product Name:	Nalpha-FMOC-L-Tryptophan
Synonyms:	N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-TRYPTOPHAN;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-TRYPTOPHAN;N-(9-FLUORENYLMETHOXYCARBONYL)-L-TRYPTOPHAN;N-9-FLUORENYLMETHYLOXYCARBONYL-L-TRYPTOPHAN;N-ALPHA-FMOC-L-TRYPTOPHAN;NALPHA-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-TRYPTOPHAN;N(^a)-Fmoc-L-tryptophan, 98%;Nalpha-FMOC-L-Tryptophan,99%
CAS:	35737-15-6
MF:	C26H22N2O4
MW:	426.46
EINECS:	252-706-5
Product Categories:	Tryptophan [Trp, W];Fmoc-Amino Acids and Derivatives;Amino Acids (N-Protected);Biochemistry;Fmoc-Amino Acids;Indoles;Protected Amino Acids;Amino Acid Derivatives;Amino Acids;Tryptophans;Fmoc-Amino acid series
Mol File:	35737-15-6.mol

Nalpha-FMOC-L-Tryptophan Chemical Properties

Melting point	182-185 °C(lit.)
alpha	-29 º (c=1,DMF)
Boiling point	541.92°C (rough estimate)
density	1.2501 (rough estimate)
refractive index	-28.5 ° (C=1, DMF)
storage temp.	2-8°C
solubility	almost transparency in Pyridine
pka	3.89±0.10(Predicted)
form	powder to crystal
color	White to Almost white
optical activity	[α]20/D 29±1°, c = 1% in DMF
BRN	4216624
InChIKey	MGHMWKZOLAAOTD-DEOSSOPVSA-N
CAS DataBase Reference	35737-15-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25-36/37/39-27-26
WGK Germany	3
HS Code	2933 99 80

MSDS Information

Provider	Language
Fmoc-Trp-OH	English
SigmaAldrich	English
ACROS	English
ALFA	English

Nalpha-FMOC-L-Tryptophan Usage And Synthesis

Chemical Properties	white to light yellow crystal powde
Uses	Nα-Fmoc-L-tryptophan is an N-Fmoc protected form of L-Tryptophan (T947210). L-Tryptophan is an essential amino acid that is important for cell proliferation and the biosynthesis of proteins. It is a precursor to Serotonin (HCl: S274980), a neurotransmitter that compound that aids in sleep and mental state. L-Tryptophan is also thought to cause eosinophilia-myalgia syndrome.

Nalpha-FMOC-L-Tryptophan Preparation Products And Raw materials

Raw materials	1H-Benzotriazole-1-carboxylic acid, 9H-fluoren-9-ylmethyl ester-->L-tryptophan monohydrochloride-->(S)-alpha-amino-1H-indole-3-propionamide-->9-FLUORENYLMETHYL PENTAFLUOROPHENYL CARBONATE-->N-(9-Fluorenylmethoxycarbonyloxy)succinimide-->L-Tryptophan-->9-Fluorenylmethyl chloroformate
Preparation Products	N-Acetyl-L-tryptophan-->INDOLICIDIN-->MELITTIN

FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID FMOC-L-TRP[2-B(OH)2] N-[(tert-Butoxy)carbonyl]-D-tryptophan FMOC-L-TRP(5-CN) FMOC-L-TRP(4,5,6,7-TETRAFLUORO) Fmoc-Trp(Boc)-OH Fmoc-Aib-OH L-Tryptophan FMOC-TRP-OSU FMOC-L-TRP(5-CHO) FMOC-TRP(MTS)-OH Nalpha-FMOC-L-Tryptophan FMOC-L-TRP(5-CH2CH2NH-BOC) 9-Fluorenylmethyl chloroformate FMOC-L-TRP(5-CH2NH-ALLOC) L-TRYPTOPHAN-N-FMOC (ALPHA-15N) Fmoc N-(9-Fluorenylmethoxycarbonyloxy)succinimide

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