1,3-Bis(trimethylsilyl)urea

1,3-Bis(trimethylsilyl)urea Basic information
General Description
Product Name:1,3-Bis(trimethylsilyl)urea
Synonyms:Urea, TMS;BIS(TRIMETHYLSILYL)UREA;BSU;N,N'-BIS(TRIMETHYLSILYL)UREA;Hexamethyl disilaurea;N N'-BIS(TRIMETHYLSILYL)UREA 98+%;Bis-(Trimethylsilyl)-Urea (BSU);Ureylenebis(trimethylsilane)
CAS:18297-63-7
MF:C7H20N2OSi2
MW:204.42
EINECS:242-177-9
Product Categories:Building Blocks;Carbonyl Compounds;Trimethylsilylazide, etc.;Chemical Synthesis;Organic Building Blocks;Ureas;Si (Classes of Silicon Compounds);Silicon Compounds (for Synthesis);Si-N Compounds;Synthetic Organic Chemistry;Blocking Agents;Protective Agents;Silazanes;Silylating Agents;Special Silanes
Mol File:18297-63-7.mol
1,3-Bis(trimethylsilyl)urea Structure
1,3-Bis(trimethylsilyl)urea Chemical Properties
Melting point 219-221 °C(lit.)
Boiling point 222°C
density 0.887
vapor pressure 0.002-1850Pa at 25℃
Fp 65°C
storage temp. Inert atmosphere,Room Temperature
solubility pyridine: soluble100mg/mL, clear to slightly hazy, colorless to light yellow
pka16.51±0.46(Predicted)
form solid
color White to Almost white
Water Solubility Reacts with water.
Sensitive Moisture Sensitive
Hydrolytic Sensitivity7: reacts slowly with moisture/water
BRN 1937452
InChIKeyMASDFXZJIDNRTR-UHFFFAOYSA-N
LogP-2.11-2.72 at 20℃
CAS DataBase Reference18297-63-7(CAS DataBase Reference)
NIST Chemistry ReferenceUrea, n,n'-bis(trimethylsilyl)-(18297-63-7)
EPA Substance Registry SystemN,N'-Bis(trimethylsilyl)urea (18297-63-7)
Safety Information
Hazard Codes F,Xn
Risk Statements 11-36/37/38-20/21/22
Safety Statements 14-16-24/25-36-26
RIDADR UN 1325 4.1/PG 2
WGK Germany 3
3-10-21
TSCA Yes
HS Code 29310095
MSDS Information
ProviderLanguage
N,N'-Bis(trimethylsilyl)urea English
ACROS English
SigmaAldrich English
ALFA English
1,3-Bis(trimethylsilyl)urea Usage And Synthesis
General DescriptionSilazane is any hydride of silicon and nitrogen having a straight or branched chain of silicon and nitrogen atoms joined by covalent bonds. By extension, the word is also used for any organic derivative of such compounds. They are analogous to siloxanes, with -NH- replacing -O-. Their individual name is dependent on the number of silicon atoms in the chemical structure. 1,3-Bis(trimethylsilyl)urea is an effective silylating agent. It is used in the pharmaceutical and in the chemical industry.
Chemical PropertiesWhite solid with mild odor
UsesN,N'-Bis(trimethylsilyl)urea is used as a reagent for the silylation of alcohols and carboxylic acids.
Flammability and ExplosibilityNotclassified
1,3-Bis(trimethylsilyl)urea Preparation Products And Raw materials
Preparation ProductsALLYLOXYTRIMETHYLSILANE-->spirobishexahydropyrimidine-->BIS(TRIMETHYLSILYL)ACETYLENEDICARBOXYLATE
Hexamethyldisilane ACETYLUREA Methanesiliconic acid sodium salt BIS-N,N'-(TRIMETHYLSILYL)-N-PHENYLUREA 1,1,3,3-Tetramethylurea (5-METHYL-1,3-BIS-TRIMETHYLSILYL)-2,4-(1H,3H-PYRIMIDINEDIONE) Heptamethyldisilazane Silicon Urea 1,3-Bis(trimethylsilyl)urea N-(Trimethylsilyl)acetamide Silicone rubber,methyl-vinyl Hexamethyldisilazane TRIMETHYLSILYL CHLOROSULFONATE

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