1-(diaminomethylidene)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea

1-(diaminomethylidene)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea Basic information
Product Name:1-(diaminomethylidene)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea
Synonyms:1-(diaminomethylidene)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea;N-[(diaminomethylidene)carbamoyl]-beta-D-ribofuranosylamine;Azacitidine Impurity 38;1-(Diaminomethylene)-3-(beta-D-ribofuranosyl)urea;Urea,N-(aminoiminomethyl)-N'-b-D-ribofuranosyl-;4-amino-1-((2S,3R,4S,5R)-;Azacitidine Amine Impurity;Urea, N-(aminoiminomethyl)-N'-β-D-ribofuranosyl-
CAS:2508-80-7
MF:C7H14N4O5
MW:234.21
EINECS:
Product Categories:
Mol File:2508-80-7.mol
1-(diaminomethylidene)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea Structure
1-(diaminomethylidene)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea Chemical Properties
Melting point 128-130°C
density 2.02±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Water (Slightly)
pka12.95±0.70(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
1-(diaminomethylidene)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea Usage And Synthesis
Uses(α)-1-D-Ribofuranosyl-3-guanylurea is a labile hydrolysis product of the antitumor nuceloside 5-Azacytidine (A796000).
1-(diaminomethylidene)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea Preparation Products And Raw materials
2'',3'',5''-Triacetyl -azacytidine 4-Amino-1-(2-O,3-O,5-O-tribenzoyl-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one Azacitidine Impurity 34 Fazarabine L-Cytidine (Z)-3-((2'-(N'-hydroxycarbaMiMidoyl)biphenyl-4-yl)Methyl)-2-oxo-2,3-dihydro-1H-benzo[d]iMidazole-4-carboxylic acid Azacitidine Impurity 3 Azacitidine Impurity 27 Azacitidine Triphosphate 4-AMINO-6-METHYL-1,3,5-TRIAZIN-2-OL Azacitidine Impurity 16 Azacitidine Impurity 35 Azacitidine Impurity 21 Azacitidine Diphosphate Azacitidine Impurity 28 1-(DiaMinoMethylene)-3-(beta-D-ribofuranosyl)urea Picrate 5-Azacytidine Azacitidine-13C-15N3

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