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| | AURANTIO-OBTUSIN Basic information |
| Product Name: | AURANTIO-OBTUSIN | | Synonyms: | 1,3,7-Trihydroxy-2,8-diMethoxy-6-Methyl-9,10-anthracenedione;Aurantio-obtusifolin;AURANTIO-OBTUSIN;1,3,7-Trihydroxy-2,8-dimethoxy-6-methylanthracene-9,10-dione;URANTIO-OBTUSIN;Aurantioobtusin, 98%, from Catsia tora Linn;9,10-Anthracenedione, 1,3,7-trihydroxy-2,8-dimethoxy-6-methyl-;67979-25-3 AURANTIO-OBTUSIN | | CAS: | 67979-25-3 | | MF: | C17H14O7 | | MW: | 330.29 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;Intermediates & Fine Chemicals;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Pharmaceuticals | | Mol File: | 67979-25-3.mol |  |
| | AURANTIO-OBTUSIN Chemical Properties |
| Melting point | 265-266 °C | | Boiling point | 594.6±50.0 °C(Predicted) | | density | 1.510±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Soluble in chloroform, DMSO and methan | | pka | 6.32±0.20(Predicted) | | form | powder | | color | Orange |
| Safety Statements | 24/25 | | HS Code | 29389090 |
| | AURANTIO-OBTUSIN Usage And Synthesis |
| Description | Aurantioobtusin is an anthraquinone originally isolated from Cassia seeds with diverse biological activities. It inhibits rat lens aldose reductase (RLAR) in vitro (IC50 = 13.6 μM). Aurantioobtusin (10 and 100 μM) activates the aryl hydrocarbon receptor (AhR) in a concentration-dependent manner. It inhibits rat platelet aggregation induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607), ADP, and collagen. Aurantioobtusin induces vasorelaxation in isolated precontracted rat mesenteric artery rings, an effect that is inhibited by the PI3K inhibitor LY290042 or inhibition of endothelial nitric oxide synthase (eNOS). It is larvicidal against A. gambiae mosquitoes (LD50 = 10 ppm). | | Uses | A compound found in herbal remedies, believed to have an effect on blood platelet aggregation and lower blood lipid count | | Definition | ChEBI: A trihydroxyanthraquinone that is 1,3,7-trihydroxy-9,10-anthraquinone which is by methoxy groups at positions 2 and 8, and by a methyl group at position 6. |
| | AURANTIO-OBTUSIN Preparation Products And Raw materials |
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