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| | Flutrimazole Basic information |
| Product Name: | Flutrimazole | | Synonyms: | flutrimazole:1-((2-fluorophenyl)-(4-fluorophenyl)phenylmethyl)-1h-IMIDAZOLE;1-[(2-Fluorophenyl)(4-fluorophenyl)(phenyl)methyl]imidazole;1-((2-fluorophenyl)(4-fluorophenyl)phenylmethyl)-1h-imidazol;1-(o-fluoro-alpha-(p-fluorophenyl)-alpha-phenylbenzyl)imidazole;flutrimazol;1-[(2-fluorophenyl)-(4-fluorophenyl)phenylmethyl]-1h-imidazole;FLUTRIMAZOLE;FLUTRIMAZOLC | | CAS: | 119006-77-8 | | MF: | C22H16F2N2 | | MW: | 346.37 | | EINECS: | | | Product Categories: | Flutrimazole;API | | Mol File: | 119006-77-8.mol |  |
| | Flutrimazole Chemical Properties |
| Melting point | 161-166℃ | | Boiling point | 457.1±40.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Practically insoluble in water, freely soluble in tetrahydrofuran, soluble in methanol. | | form | neat | | pka | 6.03±0.34(Predicted) | | color | White to Pale Yellow | | CAS DataBase Reference | 119006-77-8(CAS DataBase Reference) |
| HS Code | 2933299090 | | Toxicity | LD50 in male, female mice, male, female rats (mg/kg): >1000, >1000, 808, 1214 orally; >2000, >2000, 1079, 1446 i.p. (Vericat) |
| | Flutrimazole Usage And Synthesis |
| Description | Flutrimazole, a novel imidazole antifungal launched in Spain, is indicated for mycosis of the skin. Flutrimazole displays potent broad-spectrum of
activity against dematophytes, filamentous fungi and yeasts, saprophytic and
pathogenic to animals and humans. Similar to other imidazole and triazole antifungals,
flutrimazole exerts its biological function through inhibition of fungal lanosterol 14a-demethylase. Excellent local and systemic tolerance of flutrimazole in patients has been reported. | | Chemical Properties | White or almost white powder. | | Originator | Uriach (Spain) | | Uses | Flutrimazole is a new imidazole antifungal agent with anti-inflammatory properties as well. | | Definition | ChEBI: An imidazole antifungal agent that is imidazole in which the hydrogen attached to the nitrogen is replaced by a 2,4'-difluorotrityl group. A topical antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes,
filamentous fungi and yeasts. | | Brand name | Micetal |
| | Flutrimazole Preparation Products And Raw materials |
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