|
| | TRIETHYL 2-PHOSPHONOBUTYRATE Basic information |
| Product Name: | TRIETHYL 2-PHOSPHONOBUTYRATE | | Synonyms: | 2-PHOSPHONOBUTYRIC ACID TRIETHYL ESTER;Diethyl 1-(ethoxycarbonyl)propanephosphonate~2-Phosphonobutyric acid triethyl ester;diethyl 1-(ethoxycarbonyl)propanephosphonate;Diethyl[1-(ethoxycarbonyl)propyl]phosphonate, 98 %;Ethyl 2-(diethoxyphosphoryl)butanoate;alpha-Diethylphosphonobutanoic acid ethyl ester;Ethyl 2-(diethoxyphosphinyl)butanoate;Ethyl 2-(diethylphosphono)butyrate | | CAS: | 17145-91-4 | | MF: | C10H21O5P | | MW: | 252.24 | | EINECS: | 627-866-8 | | Product Categories: | C-C Bond Formation;Horner-Wadsworth-Emmons Reagents;Olefination | | Mol File: | 17145-91-4.mol |  |
| | TRIETHYL 2-PHOSPHONOBUTYRATE Chemical Properties |
| Boiling point | 152-154 °C14 mm Hg(lit.) | | density | 1.064 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.432(lit.) | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | form | Liquid | | color | Clear colorless | | Specific Gravity | 1.064 | | Water Solubility | Not miscible or difficult to mix with water. | | BRN | 1789280 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 29310099 |
| | TRIETHYL 2-PHOSPHONOBUTYRATE Usage And Synthesis |
| Chemical Properties | clear colorless liquid | | Uses | Reactant used for preparation of furospinosulin-1 and analogs as hypoxia-selective antitumor agents, Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimer?s drugs, phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents, PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists, notch-sparing γ-secretase inhibitors derived from PPAR agonist library and plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis. | | Uses | Reactant for preparation of:
- Furospinosulin-1 and analogs as hypoxia-selective antitumor agents
- Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimer′s drugs
- Phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents
- PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists
- Notch-sparing γ-secretase inhibitors derived from PPAR agonist library
- Plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis
- Quinone/naphthoquinone-substituted propenoic acids as inhibitors of cell growth and redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor 1 (Ape1/Ref-1)
- α-alkenyl cyclic ethers by asymmetric dehydrative cyclization of ω-hydroxy allyl alcohols catalyzed by Ru complexes of axially chiral naphthylpyridinecarboxylates
- Branched phosphonoethoxyethyl purines as new acyclic nucleoside phosphonates which inhibit Plasmodium falciparum (malarial parasite) hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT)
- Phenylpropanoic acid-type peroxisome proliferator-activated receptor pan agonists as candidate drugs for treatment of altered metabolic homeostasis
|
| | TRIETHYL 2-PHOSPHONOBUTYRATE Preparation Products And Raw materials |
|
