ChemicalBook Product Catalog Biochemical Engineering Nucleoside drugs Nucleoside Intermediates 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Basic information
Physical form Color
Product Name:5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
Synonyms:DMT-dA(bz) PhosphoraMidite;N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine 5'-CE phosphoramidite;N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite;2'DEOXYADENOSINE PHOSPHORAMADITE;2'-DEOXYADENOSINE PHOSPHORAMIDITE;dA(N-Bz) Phosphoramidite;N-blocked-5'-O-DMT 3'-CED deoxyadenosine phosphoramidite;(2R,3S,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite
CAS:98796-53-3
MF:C47H52N7O7P
MW:857.93
EINECS:685-521-7
Product Categories:Pharmaceutical;RNAi
Mol File:98796-53-3.mol
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Structure
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Chemical Properties
density 1.23 at 20℃
vapor pressure 0-0Pa at 20-50℃
storage temp. Sealed in dry,2-8°C
solubility soluble, clear
pka7.87±0.43(Predicted)
form powder or granules
color white to off-white
InChIKeyGGDNKEQZFSTIMJ-AKWFTNRHSA-N
SMILESO(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3C(=C(N=CN=3)NC(=O)C3=CC=CC=C3)N=C2)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N
LogP7.14 at 20℃
Safety Information
WGK Germany 3
HS Code 29349990
MSDS Information
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Usage And Synthesis
Physical formPowder or granules
ColorWhite to off-white
UsesN6-Benzoyl-2’-deoxy-5’-O-DMT-cytidine 3’-CE Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Preparation Products And Raw materials
Preparation ProductsN6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
Trimethoxypropylsilane AMINO-MODIFIER-C 6-DA CEP Benzoyl peroxide 5'-O-FDMT-N6-BENZOYL-2'-DEOXYADENOSINE CEP Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI) Vidarabine ADENOSINE 5'-TRIPHOSPHATASE 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite DMT-2μ-O-Me-rA(bz) amidite 2'-Deoxyadenosine Adenosine 3-Chloropropyltriethoxysilane 3-Aminopropyltriethoxysilane Cyclic AMP Benzoyl chloride 3-Chloropropyltrimethoxysilane 2'-Deoxyadenosine monohydrate 3-Mercaptopropyltriethoxysilane
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