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| | PSEUDOLARIC ACID B Basic information |
| Product Name: | PSEUDOLARIC ACID B | | Synonyms: | Pseudolaric acid;Pseudolaric Acid B
(PAB);Pseudolaric Acid B(PBA);-1,3-pentadienyl)3,4,4a,5,6,9-hexahydro-3-methyl-1-oxo-,7-methylester,(3-al;1h-4,9a-ethanocyclohepta(c)pyran-7-carboxylicacid,4a-(acetyloxy)-3-(4-carboxy;pha(1e,3e),4-alpha,4a-alpha,9a-alpha)-(-)-(9ci);PSEUDOLARIC ACID B;PLAB | | CAS: | 82508-31-4 | | MF: | C23H28O8 | | MW: | 432.46 | | EINECS: | 231-291-4 | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors | | Mol File: | 82508-31-4.mol |  |
| | PSEUDOLARIC ACID B Chemical Properties |
| Melting point | 166°C | | Boiling point | 466.14°C (rough estimate) | | density | 1.2108 (rough estimate) | | refractive index | 1.4480 (estimate) | | storage temp. | 2-8°C | | solubility | methanol: soluble1mg/mL, clear, colorless | | form | powder or crystals | | pka | 4.52±0.19(Predicted) | | color | white to off-white | | InChIKey | VDGOFNMYZYBUDT-YCONPBHISA-N |
| | PSEUDOLARIC ACID B Usage And Synthesis |
| Description | Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections. Moreover, PAB has diverse effects that are relevant to cancer therapy, including inducing apoptosis of cancer cells (IC50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth in vivo. | | Uses | (-)-Pseudolaric Acid B is a diterpenoid posessing an immunomodulatory effect. It acts as an immunosuppressant in vitro/vivo however does show some cytotoxicity. Anti-tumor agent as well. | | Definition | ChEBI: Pseudolaric acid B is a diterpene lactone. |
| | PSEUDOLARIC ACID B Preparation Products And Raw materials |
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