N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Basic information

Product Name:	N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
Synonyms:	4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol;4OHNDtam;E/Z Endoxifen;N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture);4-hydroxy-N-desmethyltamoxifen;4-[(E)-1-[4-(2-methylaminoethoxy)phenyl]-2-phenyl-but-1-enyl]phenol;4-[(Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol;N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) see H938500
CAS:	110025-28-0
MF:	C25H27NO2
MW:	373.49
EINECS:
Product Categories:	Aromatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:	110025-28-0.mol

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Chemical Properties

Melting point	63-72°C
Boiling point	519.3±50.0 °C(Predicted)
density	1.099±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Chloroform, Dichloromethane, DMSO, Methanol
pka	9.38±0.15(Predicted)
form	Solid
color	Light Brown to Light Purple

Safety Information

MSDS Information

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Usage And Synthesis

Chemical Properties	Brown Foam
Uses	A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast ca
Uses	A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.
storage	Store at +4°C

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Preparation Products And Raw materials

Raw materials

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