7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Basic information
Product Name:7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
Synonyms:TIMTEC-BB SBB003016;1-CYCLOPROPYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLONE-3-CARBOXYLIC ACID;1-CYCLOPROPYL-6-FLUORO-7-CHLORO-1,4-DIHYDRO-4-OXO-3-QUINOLINIC CARBOXYLIC ACID;7-CHLORO-1-CYCLOPROPYL-1,4-DIHYDRO-6-FLUOROQUINOL-4-ONE-3-CARBOXYLIC ACID;7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID;7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID;7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID;7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXOHYDROQUINOLINE-3-CARBOXYLIC ACID
CAS:86393-33-1
MF:C13H9ClFNO3
MW:281.67
EINECS:405-050-0
Product Categories:alkyl chloride | alkyl Fluorine| carboxylic acid;Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles;Metabolites & Impurities;Ciprofloxacin;86393-33-1
Mol File:86393-33-1.mol
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Structure
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Chemical Properties
Melting point 242-245 °C(lit.)
Boiling point 467.3±45.0 °C(Predicted)
density 1.652±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form neat
pka6.36±0.41(Predicted)
color Off-White to Light Yellow
InChIKeyISPVACVJFUIDPD-UHFFFAOYSA-N
CAS DataBase Reference86393-33-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38-52/53
Safety Statements 26-36-61-22
WGK Germany 2
RTECS VB1993795
HazardClass IRRITANT
HS Code 29334900
MSDS Information
ProviderLanguage
Q-Acid English
SigmaAldrich English
ACROS English
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Usage And Synthesis
Chemical PropertiesOff-White Crystalline Powder
Uses7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid (Ciprofloxacin EP Impurity A) is a metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial.
UsesAn intermediate in the synthesis of Ciprofloxacin, a fluorinated quinolone antibacterial
General Description7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, also known as fluoroquinolonic acid, can be prepared from ethyl 2,4-dichloro-5-fluorobenzoylacetate. It is formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug.
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Preparation Products And Raw materials
Preparation ProductsCyhalothrin-->Ciprofloxacin Related CoMpound-->DESETHYLENE CIPROFLOXACIN, HYDROCHLORIDE-->7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER-->Enrofloxacin
3-METHOXYPROPIONIC ACID Chloromethyl isopropyl carbonate Propiconazole 5,6,7,8-TETRAHYDROISOQUINOLINE 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid Ciprofloxacin hydrochloride Ethyl 2-(Chlorosulfonyl)acetate Ascoric Acid 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid chloroquinoline Ciprofloxacin lactate (1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID Clioquinol CARBOXYLIC ACID phosphoric acid (3-THIOPHEN-2-YLMETHYL-5-THIOXO-1,5-DIHYDRO-[1,2,4]TRIAZOL-4-YL)-ACETIC ACID fluoro jade Dihydromyrcenol

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