ChemicalBook Product Catalog Organic Chemistry Amides Amino compound tert-Butyl 2-(aminomethyl)phenylcarbamate

tert-Butyl 2-(aminomethyl)phenylcarbamate

tert-Butyl 2-(aminomethyl)phenylcarbamate Basic information
Product Name:tert-Butyl 2-(aminomethyl)phenylcarbamate
Synonyms:2-(Aminomethyl)aniline, 1-BOC protected;2-[(tert-Butoxycarbonyl)amino]benzylamine, tert-Butyl [2-(aminomethyl)phenyl]carbamate;tert-Butyl N-[2-(aminomethyl)phenyl]carbamate;2-(tert-Butoxycarbonylamino)benzylamine;2-(Boc-amino)benzylamine;2-(Aminomethyl)-N-Boc-aniline;TERT-BUTYL 2-(AMINOMETHYL)PHENYLCARBAMATE;ert-Butyl N-(2-aminomethylphenyl)carbamate
CAS:849020-94-6
MF:C12H18N2O2
MW:222.28
EINECS:
Product Categories:Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Polyamines;Protected Amines
Mol File:849020-94-6.mol
tert-Butyl 2-(aminomethyl)phenylcarbamate Structure
tert-Butyl 2-(aminomethyl)phenylcarbamate Chemical Properties
Boiling point 238-242℃
density 1.054g/mLat 25℃
Fp 71°C
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka13.67±0.70(Predicted)
Safety Information
Hazard Codes Xn
Risk Statements 22-43
Safety Statements 36/37
RIDADR NA 1993 / PGIII
WGK Germany 3
HS Code 2921490090
MSDS Information
tert-Butyl 2-(aminomethyl)phenylcarbamate Usage And Synthesis
UsesTert-Butyl 2-(aminomethyl)phenylcarbamate can be used as reactant for Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize)
UsesReactant for:
  • Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize) strategy
  • Preparation of hydroquinazoline scaffolds via microwave-promoted Ugi reaction and cyclization
  • Preparation of pyrazinone inhibitors of mast cell tryptase
tert-Butyl 2-(aminomethyl)phenylcarbamate Preparation Products And Raw materials
tert-butyl 6-(aminomethyl)-2,3-dihydrobenzo[b][1,4]dioxin-5-ylcarbamate 5-AMINO-2,3,4,5-TETRAHYDRO-BENZO[B]AZEPINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER tert-butyl 2-(aminomethyl)-3-(trifluoromethoxy)phenylcarbamate 2-(aminomethyl)-3-(tert-butoxycarbonylamino)benzoate 4-AMINO-3-(FMOC-AMINOMETHYL)-BENZOIC ACID [2-(1-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER FMOC-LYS(MEABZ-BOC)-OH tert-butyl 6-(aminomethyl)-2,3-dihydrobenzo[b][1,4]dioxin-7-ylcarbamate tert-butyl 2-(aminomethyl)-5-(trifluoromethoxy)phenylcarbamate (2-PIPERIDIN-2-YL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER [2-(MORPHOLINE-4-CARBONYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER tert-Butyl 2-(aminomethyl)phenylcarbamate FMOC-LYS(RETRO-ABZ-BOC)-OH Tert-butyl 2-(aminomethyl)-4,5-dimethoxyphenylcarbamate tert-butyl 2-(aminomethyl)-5-methoxyphenylcarbamate TERT-BUTYL 4-AMINO-3,4-DIHYDROQUINOLINE-1(2H)-CARBOXYLATE 4-AMINO-1-N-BOC-5,7-DICHLORO-1,2,3,4-TETRAHYDROQUINOLINE FMOC-LYS(RETRO-ABZ-N-ME-BOC)-OH
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