Ethyl 4,6-dichloronicotinate

Ethyl 4,6-dichloronicotinate Basic information
Uses
Product Name:Ethyl 4,6-dichloronicotinate
Synonyms:4,6-Dichloronicotinic acid ethyl ester ,97%;ethyl 4,6-dichloronicotinate (en);Ethyl 4,6-dichloronicotinate ,97%;ethyl 4,6-dichloropyridine-3-carboxylate;3-Pyridinecarboxylicacid,4,6-dichloro-,ethylester;4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER;4,6-DICHLORONICOTINIC ACID ETHYL ESTER;ETHYL 4,6-DICHLORONICOTINATE
CAS:40296-46-6
MF:C8H7Cl2NO2
MW:220.05
EINECS:
Product Categories:Pyridine series;Boronic Acid
Mol File:40296-46-6.mol
Ethyl 4,6-dichloronicotinate Structure
Ethyl 4,6-dichloronicotinate Chemical Properties
Melting point 32-34°
Boiling point 85°C/0.01mmHg(lit.)
density 1.367±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in methanol.
pka-1.24±0.10(Predicted)
form Liquid
color Yellow
InChIInChI=1S/C8H7Cl2NO2/c1-2-13-8(12)5-4-11-7(10)3-6(5)9/h3-4H,2H2,1H3
InChIKeyAAUBVINEXCCXOK-UHFFFAOYSA-N
SMILESC1=NC(Cl)=CC(Cl)=C1C(OCC)=O
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36
HazardClass IRRITANT
HS Code 29339900
MSDS Information
Ethyl 4,6-dichloronicotinate Usage And Synthesis
UsesEthyl 4,6-Dichloronicotinate acts as a reactant in the preparation of (acylamino)aminonaphthyridinones as novobiocin analogs and Hsp90 inhibitors, their antitumor activities in human breast cancer cell lines, and the effects on aptoptosis and cell cycle advancement of selected compounds.
Chemical PropertiesWhite solid
UsesEthyl 4,6-dichloronicotinate, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is also used as a fine chemical intermediate.
Ethyl acetoacetate Ethyl nicotinate 2,6-Dichloronicotinic acid Ethanol Ethyl pyruvate Ethyl formate 2,5-Dichloronicotinic acid 6-Chloronicotinic acid Ethylparaben 5,6-Dichloronicotinic acid 4,6-Dichloronicotinic acid Ethyl acetate Ethyl oleate CARBOXYLIC ACID 2-Chloronicotinic acid Ethyl acrylate Thionyl chloride Ethyl cyanoacetate

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