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| | Centchroman Basic information |
| Product Name: | Centchroman | | Synonyms: | Centchroman;1-[2-[p-(trans-7-Methoxy-2,2-diMethyl-3-phenyl-
4-chroManyl)phenoxy]ethyl]pyrrolidine;3,4-trans-2,2-DiMethyl-3-phenyl-4-[p-(β-
py;rel-1-[2-[4-[(3R,4R)-3,4-dihydro-7-Methoxy-2,2-diMethyl-3-phenyl-2H-1-benzopyran-4-yl]phenoxy]ethyl]pyrrolidine;Pyrrolidine, 1-[2-[4-[(3R,4R)-3,4-dihydro-7-methoxy-2,2-dimethyl-3-phenyl-2H-1-benzopyran-4-yl]phenoxy]ethyl]-, rel-;Centchroman ISO 9001：2015 REACH | | CAS: | 31477-60-8 | | MF: | C30H35NO3 | | MW: | 457.6 | | EINECS: | 256-846-9 | | Product Categories: | Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 31477-60-8.mol |  |
| | Centchroman Chemical Properties |
| Melting point | 99-101° | | Boiling point | 563.39°C (rough estimate) | | density | 1.1065 (rough estimate) | | refractive index | 1.6310 (estimate) | | storage temp. | 2-8°C | | solubility | Soluble in DMSO | | pka | 9.61±0.20(Predicted) | | form | oil | | color | colorless to light brown |
| | Centchroman Usage And Synthesis |
| Description | Centchroman is a new, weekly, orally active contraceptive with weak estrogenic and
potent antiestrogenic properties.It is reported to be the first non-hormonal,
non-steroidal oral contraceptive. Centchroman acts by inhibiting the implantation of
fertilized eggs in the uterus. With the exception of longer menstrual cycles, no side
effects have been reported. Another indication under study is the treatment of hormone
dependent breast cancer. | | Originator | Central Drug Research Institute (India) | | Uses | Centchroman is an estrogen antagonist. Centchroman is a synthetic nonsteroidal postcoital antifertility agent. | | Brand name | Choice-7 |
| | Centchroman Preparation Products And Raw materials |
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