β-Tocopherol

β-Tocopherol Basic information
Product Name:β-Tocopherol
Synonyms:5,8-DIMETHYLTOCOL;RAC-BETA-TOCOPHEROL;beta-tocopherol;3,4-dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol;Tocopherol,rac-b-;(2R)-2,5,8-trimethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol;rac-beta-Tocopherol (5,8-DiMethyltocol);β-Tocopherol (Racemic Mixture)
CAS:148-03-8
MF:C28H48O2
MW:416.68
EINECS:205-708-5
Product Categories:TF - TOChromatography;Alphabetic;Food&Beverage Standards;Vitamins/CoFactors/Enzymes
Mol File:148-03-8.mol
β-Tocopherol Structure
β-Tocopherol Chemical Properties
Melting point <25℃
Boiling point 474.94°C (rough estimate)
density 0.9882 (rough estimate)
refractive index 1.4480 (estimate)
Fp -23 °C
storage temp. 2-8°C
solubility Chloroform (Sparingly), Ethanol (Slightly), Ethyl Acetate (Slightly), Methanol (
form Oil
pka11.05±0.40(Predicted)
color Colourless to Yellow
InChIKeyWGVKWNUPNGFDFJ-UHFFFAOYSA-N
LogP10.724 (est)
EPA Substance Registry System2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-rel- (148-03-8)
Safety Information
Hazard Codes F,Xn,N
Risk Statements 11-38-48/20-51/53-62-67-65
Safety Statements 36/37-61-62-16
RIDADR UN1208 3/PG 2
WGK Germany 3
MSDS Information
β-Tocopherol Usage And Synthesis
Description(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an EC50 value of 68.2 μM. (±)-β-Tocopherol (100 μM) inhibits LPS-induced COX-2 gene expression in mouse RAW 264.7 macrophage cells. Unlike (±)-α-tocopherol , (±)-β-tocopherol does not inhibit smooth muscle cell proliferation, decrease PKC activity, increase phosphoprotein phosphatase 2A (PP2A) activity, or modify expression of the α-tropomyosin gene. [Matreya, LLC. Catalog No. 1071]
UsesOne of the naturally occurring forms of Vitamin E. Is biologically less active than α-Tocopherol. This is the racemic mixture of all stereoisomers.
DefinitionChEBI: Beta-tocopherol is a tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 5 and 8. While it is found in low concentrations in many vegetable oils, only cottonseed oil contains significant amounts. It has a role as a plant metabolite and a food component. It is a vitamin E and a tocopherol.
β-Tocopherol Preparation Products And Raw materials
TOCORRETINATE EPC-K(1) Tocofibrate DL-ALPHA-TOCOPHEROL HYDROGEN SUCCINATE Vitamin E D-alpha-Tocopheryl acetate DL-α-Tocopherol Vitamin E nicotinate β-Tocopherol Tocofenoxate Vitamin E DL-ALPHA-TOCOPHEROL ACETATE DL-ALPHA-TOCOPHEROLOXYPROPYLDIMETHYLCHLOROSILANE (+/-)-ALPHA-TOCOPHEROL PHOSPHATE DISODIUM SALT LABOTEST-BB LT00244777 D-α-Tocopherol succinate Tocoretinate TOCOPHERYL LINOLEATE

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