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| | 2-Quinolinol Basic information |
| Product Name: | 2-Quinolinol | | Synonyms: | 2-Oxo-1,2-dihydroquinoline;1,2-Dihydroquinolin-2-one;2-Hydroxyquinoline, 99% 10GR;Carbostyril
2-Hydroxyquinoline;Quinolin-2-ol, 2-Hydroxy-1-azanaphthalene, Carbostyril;2-quinolinol:2-hydroxyQUINOLINE: carbostyril;2-Quinolinol, Carbostyril;2(1h)-quinolinone | | CAS: | 59-31-4 | | MF: | C9H7NO | | MW: | 145.16 | | EINECS: | 200-420-6 | | Product Categories: | Hydroxyquinolines;Quinolines;bc0001 | | Mol File: | 59-31-4.mol |  |
| | 2-Quinolinol Chemical Properties |
| Melting point | 198-199 °C (lit.) | | Boiling point | 264.27°C (rough estimate) | | density | 1.1555 (rough estimate) | | refractive index | 1.4500 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | alcohol: soluble(lit.) | | form | Powder | | pka | -0.31, 11.76(at 20℃) | | color | White to light purple or purple-brownish | | Water Solubility | 1.052g/L(20 ºC) | | Merck | 14,1825 | | BRN | 2855 | | CAS DataBase Reference | 59-31-4(CAS DataBase Reference) | | NIST Chemistry Reference | 2(1H)-Quinolinone(59-31-4) | | EPA Substance Registry System | 2(1H)-Quinolinone (59-31-4) |
| | 2-Quinolinol Usage And Synthesis |
| Chemical Properties | white to light purple or purple-brownish powder | | Uses | 2-Hydroxyquinoline was used to obtain the design of the platinum(IV) complexes with intense bands shifted towards longer wavelengths. The Pt(IV) complexes are inert stable prodrugs that were photoactivated to produce Pt(II) species with promising anticancer activity. | | Definition | ChEBI: A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2. | | Synthesis Reference(s) | Synthesis, p. 739, 1975 DOI: 10.1055/s-1975-23918 | | General Description | 2-Hydroxyquinoline is a specific inhibitor of plaque paraoxonase1 (PON1). | | Purification Methods | Crystallise it from MeOH. It has m 200-201o after sublimation in a vacuum. The picrate has m 132o after crystallisation from Et2O. [Gibson et al. J Chem Soc 4340 1955, Beilstein 21 III/IV 1057, 21/8 V 217.] |
| | 2-Quinolinol Preparation Products And Raw materials |
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