ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Phenylalanine derivatives L-4-Fluorophenylalanine

L-4-Fluorophenylalanine

L-4-Fluorophenylalanine Basic information
Product Name:L-4-Fluorophenylalanine
Synonyms:(S)-2-AMINO-3-(4-FLUORO-PHENYL)-PROPIONIC ACID;RARECHEM BK PT 0031;P-FLUORO-L-PHENYLALANINE;P-FLUORO-PHENYLALANINE;L-4-FLUOROPHE;L-4-FLUOROPHENYLALANINE;H-L-PHE(4-F)-OH;H-PHE(4-F)-OH
CAS:1132-68-9
MF:C9H10FNO2
MW:183.18
EINECS:145-896-5
Product Categories:Phenylalanine analogs and other aromatic alpha amino acids;Phenylalanine [Phe, F];Unusual Amino Acids;Amino hydrochloride;a-amino;Non-natural amino acids;Amino Acids
Mol File:1132-68-9.mol
L-4-Fluorophenylalanine Structure
L-4-Fluorophenylalanine Chemical Properties
Melting point ~255 °C (dec.)
alpha -26.5 º (c=1, H2O 25 ºC)
Boiling point 313.3±32.0 °C(Predicted)
density 1.1939 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder to crystal
pka2.20±0.10(Predicted)
color White to Almost white
Water Solubility Soluble in water and 0.5M HCl (50 mg/ml).
BRN 2416148
CAS DataBase Reference1132-68-9(CAS DataBase Reference)
Safety Information
Safety Statements 23-24/25
WGK Germany 3
RTECS DW1765000
Hazard Note Harmful
HS Code 29224999
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
L-4-Fluorophenylalanine Usage And Synthesis
Chemical Propertieswhite to off-white powder
Uses4-Fluoro-L-phenylalanine is a substrate for tyrosine hydroxylase (TH) that has been used to study the regulation of that enzyme.
DefinitionChEBI: A L-phenylalanine derivative that is L-phenylalanine in which the hydrogen at position 4 on the benzene ring is replaced by a fluoro group.
Purification MethodsIt is recrystallised from aqueous EtOH. The (R)-N-acetyl derivative has m 142-145o, [] D -38.6o (c 8, EtOH). [Bennett & Nieman J Am Chem Soc 72 1800 1950, Beilstein 14 III 1268.]
Phenprobamate Fluorine D-2,4,5-TRIFLUOROPHE L-Phenylalanine BOC-D-2,4,5-TRIFLUOROPHE EC 2.6.1.2 ALPHA-(4-FLUOROBENZYL)-(R)-PROLINE 3,4-Difluoro-D-phenylalanine DL-Phenylalanine L-Alanine BOC-D-3,4,5-TRIFLUOROPHENYLALANINE FMOC-D-4-Fluorophe L-4-Fluorophenylalanine L-Alanine D-Alanine H-P-FLUORO-D-PHE-OME HCL BOC-L-PENTAFLUOROPHENYLALANINE D-Phenylalanine
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