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| | Ketanserin Basic information |
| | Ketanserin Chemical Properties |
| Melting point | 227-235°C | | density | 1.280±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | DMF: 10 mg/mL, clear, colorless | | form | Solid | | pka | 7.5(at 25℃) | | color | White to Off-White | | Merck | 14,5296 | | CAS DataBase Reference | 74050-98-9(CAS DataBase Reference) |
| WGK Germany | 3 | | RTECS | VA1411190 | | HS Code | 29339900 |
| | Ketanserin Usage And Synthesis |
| Description | Ketanserin is an antihypertensive agent with antagonist properties at both the
serotonin-S2 and α1-adrenergic receptors. Its mechanism of action, while still
controversial, may involve interactions at both of these loci. | | Chemical Properties | Off-White Solid | | Originator | Janssen (Belgium) | | Uses | An antihypertensive, with affinity for multiple GPCR receptors. | | Uses | receptor antagonist | | Definition | ChEBI: A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group. | | Brand name | SEREFREX | | Purification Methods | It has been purified by recrystallisation from 4-methyl-3-pentanone [Peeters et al. Cryst Structure Commun 11 375 1982, Kacprowicz et al. J Chromatogr 272 417 1983, Davies et al. J Chromatogr 275 232 1983]. It is an antihypertensive. |
| | Ketanserin Preparation Products And Raw materials |
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