2-Ethoxybenzamide

2-Ethoxybenzamide Basic information
Product Name:2-Ethoxybenzamide
Synonyms:2-ethoxy-benzamid;Salicylamideo-ethylether;Trancalgyl;ETHENZAMIDE;2-ETHOXYBENZAMIDE;2-ETHOXYBENZOYLAMIDE;ETHENZAMIDE/ETHOXYBENZAMIDE;2-ETHOXYBENZAMIDE(ETHENZAMIDE)
CAS:938-73-8
MF:C9H11NO2
MW:165.19
EINECS:213-346-4
Product Categories:Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;API's;Amides;Carbonyl Compounds;Organic Building Blocks
Mol File:938-73-8.mol
2-Ethoxybenzamide Structure
2-Ethoxybenzamide Chemical Properties
Melting point 132-134 °C (lit.)
Boiling point 293.03°C (rough estimate)
density 1.1603 (rough estimate)
refractive index 1.5620 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Dichloromethane (Slightly)
pka15.62±0.50(Predicted)
form Granular Crystalline Powder
color White to almost white
Water Solubility <0.1 g/100 mL at 16 ºC
Merck 14,3731
CAS DataBase Reference938-73-8(CAS DataBase Reference)
NIST Chemistry ReferenceEthenzamide(938-73-8)
EPA Substance Registry SystemEthenzamide (938-73-8)
Safety Information
Safety Statements 24/25
WGK Germany 2
RTECS CU4381000
TSCA Yes
HS Code 29242995
ToxicityLD50 orally in mice: 1160 mg/kg (Starmer)
MSDS Information
ProviderLanguage
o-Ethoxybenzamide English
ACROS English
ALFA English
2-Ethoxybenzamide Usage And Synthesis
Chemical PropertiesWHITE TO ALMOST WHITE GRANULAR CRYSTALLINE POWDER
OriginatorEthenzamide,Tongxiang Hengda
DefinitionChEBI: Ethenzamide is an organic molecular entity.
Manufacturing Process500 g of salicylic amide are dissolved in 1.5 L of 10% alcohol by means of 146 g of sodium hydroxide. 560 g diethyl sulphate are added, the mixture is frequently shaken during four hours and kept cold. 20 hours later the 2- ethoxy-benzamide is precipitated in a gritty state and is removed by suction and dried at 50°-100°C. The yield is 540 g or about 90%. MP: 130°C.
Therapeutic FunctionAnalgesic
General DescriptionWhite or almost-white crystalline powder. Almost odorless. Tasteless.
Air & Water ReactionsInsoluble in water.
Reactivity Profile2-Ethoxybenzamide is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health HazardACUTE/CHRONIC HAZARDS: When heated to decomposition 2-Ethoxybenzamide emits toxic fumes of nitrogen oxides.
Fire HazardFlash point data for 2-Ethoxybenzamide are not available; however, 2-Ethoxybenzamide is probably combustible.
Chlorantraniliprole N,N'-Ethylenebis(stearamide) Acetaminophen 4-t-Butylbenzamide 2-Phenylacetamide Acetamide MERSALYL ACID N-ALLYL-2-(CARBOXYMETHOXYL)BENZAMIDE 2-Ethoxybenzamide NAPHTHOL AS-D ACETATE 3-CHLOROACETOXY-2-NAPHTHOIC ACID ANILIDE Benzamide Thioacetamide 2-Cyanoacetamide p-Aminobenzamide NAPHTHOL AS ACETATE 2-Ethoxyphenol chlorthenoxazine

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