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Cabozantinib impurity DX2

Cabozantinib impurity DX2 Basic information
Product Name:Cabozantinib impurity DX2
Synonyms:N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluoro-2-hydroxyphenyl)-1,1-cyclopropanedicarboxamide;Cabozantinib impurity DX2;Cabozantinib impurity 65;1,1-Cyclopropanedicarboxamide, N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluoro-2-hydroxyphenyl)-;N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-2-hydroxyphenyl)cyclopropane-1,1-dicarboxamide;Cabozantinib Metabolite M9;Cabozantinib Impurity 78;Tributyl Acetylcitrate Impurity 1 (Tributyl Acetylcitrate EP Impurity A)
CAS:1628530-38-0
MF:C28H24FN3O6
MW:517.51
EINECS:
Product Categories:
Mol File:1628530-38-0.mol
Cabozantinib impurity DX2 Structure
Cabozantinib impurity DX2 Chemical Properties
Boiling point 781.8±60.0 °C(Predicted)
density 1.447±0.06 g/cm3(Predicted)
pka8.42±0.40(Predicted)
Safety Information
MSDS Information
Cabozantinib impurity DX2 Usage And Synthesis
Uses2-??Hydroxy Cabozantinib is a metabolite of cabozantinib (CAS# 849217-68-1), which is a tyrosine kinase inhibitor and an anticancer drug used in the treatment of thyroid cancer, renal cell carcinoma and hepatocellular carcinoma.
Cabozantinib impurity DX2 Preparation Products And Raw materials
Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]- Cabozantinib impurity 1DYH 1,1-Cyclopropanedicarboxamide, N,N'-bis[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]- Cabozantinib Malate Cyclopropanecarboxylic acid, 1-[(phenylaMino)carbonyl]- Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- 1,1-Cyclopropanedicarboxamide,N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-phenyl- N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluoro-3-hydroxyphenyl)-1,1-cyclopropanedicarboxamide Cyclopropanecarboxylic acid, 1-[[[4-[[7-methoxy-6-(sulfooxy)-4-quinolinyl]oxy]phenyl]amino]carbonyl]- 1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid Cabozantinib Impurity EXA N,N'-Bis(4-hydroxyphenyl)hydrazine 1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl- 4-chloro-6,7-dimethoxyquinoline N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide Cabozantinib Impurity DM Cabozantinib Impurity 5 4-Aminoveratrole
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