4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide

4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide Basic information
Product Name:4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
Synonyms:N-[6-CHLORO-5-(2-METHOXYPHENOXY)-(2,2-BIPYRIMIDINE)4-4-YL]-(1,1-DIMETHYLETHYL)-BENZENESULFONAMIDE;4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide;n-[6-chloro-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)benzenesulfonamide;N-[6-chloro-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)-B;Benzenesulfonamide, N-[6-chloro-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)- (bosentan intermediate);Benzenesulfonamide, N-[6-Chloro-5-(2-Methoxyphenoxy)[2,2'-Bi-Pyrimidin]-4-Yl]-4-(1,1-Dimethylethyl)-(9ci);4-tert-Butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-(2;Benzenesulfonamide, N-[6-chloro-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)-
CAS:150727-06-3
MF:C25H24ClN5O4S
MW:526.01
EINECS:1312995-182-4
Product Categories:pyrimidine;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals
Mol File:150727-06-3.mol
4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide Structure
4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide Chemical Properties
Melting point 212-214°C
Boiling point 676.7±65.0 °C(Predicted)
density 1.348±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka3.67±0.10(Predicted)
form Solid
color White to Pale Yellow
Safety Information
HS Code 2935909550
MSDS Information
4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide Usage And Synthesis
Chemical PropertiesLight Pale Yellow Sold
UsesAn intermediate of Bosentan, which is a mixed endothelin receptor antagonist. Bosentan USP Related Compound A.
4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide Preparation Products And Raw materials
Preparation ProductsBosentan-->Bosentan Impurity 1
4-Methoxybenzyl cyanide 4-Methoxybenzyl alcohol Cyhalofop-butyl tert-Butyl acetate Guaiacol Buprofezin Anisole tert-Butanol (Trifluoromethoxy)benzene 4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide Diethylene glycol monobutyl ether Butyl acrylate Butyl acetate p-Anisidine 2,2'-BIPYRIMIDINE 4-Methoxyphenol 4-Amino-6-chloro-5-methoxypyrimidine 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-chloro-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide

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