Canagliflozin-10

Canagliflozin-10 Basic information
Product Name:Canagliflozin-10
Synonyms:(2R,3R,4R,5R)-2-((R)-1,2-dihydroxyethyl)-5-(3-((5-(4- fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl) tetrahydrofuran-3,4-diol;Canagliflozin-10;Canagliflozin impurity 9/(2R,3R,4R,5R)-2-((R)-1,2-dihydroxyethyl)-5-(3-((5-(4- fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl) tetrahydrofuran-3,4-diol;D-Galactitol, 1,4-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-;Canagliflozin Furanose Form (Mixture of Anomers);canagliflozin impurities613;canagliflozin impurities3
CAS:2161394-94-9
MF:C24H25FO5S
MW:444.52
EINECS:
Product Categories:
Mol File:2161394-94-9.mol
Canagliflozin-10 Structure
Canagliflozin-10 Chemical Properties
Melting point >53°C (dec)
Boiling point 673.5±55.0 °C(Predicted)
density 1.375±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
pka13.56±0.70(Predicted)
form Solid
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
Canagliflozin-10 Usage And Synthesis
Uses1-C-[3-[[5-(4-Fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucose is an intermediate used in the synthesis of Canagliflozin (C175190). Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor; Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
Canagliflozin-10 Preparation Products And Raw materials
Canagliflozin Pioglitazone hydrochloride Canagliflozin Impurity 45 2-(4-fluorophenyl)-5-(2-Methylbenzyl)thiophene Canagliflozin Impurity 27 Canagliflozin heMihydrate Canagliflozin Impurity 15 2-(5-broMo-2-Methylbenzyl)-5-phenylthiophene Canagliflozin Impurity 41 (1R,2S,3R,4R,5R)-1-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)hexane-1,2,3,4,5,6-hexaol Canagliflozin Impurity 12 Canagliflozin Dimer Impurity 2 Canagliflozin Impurity 16 2-(1,2-dihydroxyethyl)-5-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)tetrahydrofuran-3,4-diol Canagliflozin Impurity 20 Canagliflozin Impurity 25 Canagliflozin D4 Canagliflozin Impurity 63

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