4-(2-Aminoethyl)benzenesulfonamide

4-(2-Aminoethyl)benzenesulfonamide Basic information
Uses
Product Name:4-(2-Aminoethyl)benzenesulfonamide
Synonyms:P-(2-AMINOETHYL)BENZENESULFONAMIDE;OTAVA-BB BB7020410047;TIMTEC-BB SBB003544;LABOTEST-BB LT00080735;4-(2-AMINOETHYL)BENZENESULFONAMIDE;4-(2-AMINOETHYL)BENZENE SULFONMIDE;4-(2-AMINOETHYL)BENZENE SULPHONAMIDE;4-(2-Ethylamino) Benzene Sulfonamide
CAS:35303-76-5
MF:C8H12N2O2S
MW:200.26
EINECS:252-501-0
Product Categories:SULFONAMIDE;Benzene derivates;(intermediate of glibenclamide,glipizide,gliquido;Organic Building Blocks;Sulfonamides/Sulfinamides;Sulfur Compounds
Mol File:35303-76-5.mol
4-(2-Aminoethyl)benzenesulfonamide Structure
4-(2-Aminoethyl)benzenesulfonamide Chemical Properties
Melting point 150-152 °C (lit.)
Boiling point 387.4±44.0 °C(Predicted)
density 1.2581 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index 1.5690 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka10.16±0.10(Predicted)
form Solid
color White
Water Solubility 15.5g/L at 20℃
LogP-3.1 at 19.8℃
CAS DataBase Reference35303-76-5(CAS DataBase Reference)
Safety Information
Hazard Codes C,Xi,Xn
Risk Statements 34-22-36/37/38-20/21/22
Safety Statements 45-36/37/39-26-36-24/25
RIDADR UN3259
WGK Germany 3
Hazard Note Irritant
HazardClass 8
PackingGroup III
HS Code 29350090
MSDS Information
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4-(2-Aminoethyl)benzenesulfonamide English
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4-(2-Aminoethyl)benzenesulfonamide Usage And Synthesis
Uses4-(2-Aminoethyl)benzenesulfonamide is used as the starting material in the synthesis of Des(5-methylpyrazinecarbonyl) trans-4-Methyl Glipizide (D292605); a degradation product of Glimepiride (G410150) which is a sulfonylurea hypoglycemic agent and an antidiabetic. 4-(2-Aminoethyl)benzenesulfonamide is also used as a reagent in the synthesis of deorphaning pyrrolopyrazines as potent multi-target antimalarial agents.
Chemical Propertieswhite to yellowish crystalline powder
Uses4-(2-Aminoethyl)benzenesulfonamide was used to develop a model system to study the implementation of a microfluid chip required for Fourier transform measurements of biochemical interactions.
General DescriptionThe human hepatocellular carcinoma (HCC) cells were treated with its inhibitor 4-(2-aminoethyl)benzenesulfonamide.
Flammability and ExplosibilityNotclassified
4-(2-Aminoethyl)benzenesulfonamide Preparation Products And Raw materials
Preparation Products4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide
3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide GLIMEPIRIDE RELATED COMPOUND C (20 MG) (GLIMEPIRIDE URETHANE) Glimepiride Impurity 19 rac trans-Hydroxy Glimepiride-D5 GLIBENCLAMIDE, [CYCLOHEXYL-2,3-3H(N)]- 4-(1-AMINOETHYL)BENZENESULFONAMIDE 4-(2-AMINOETHYL)BENZENESULFONAMIDE MONOHYDROCHLORIDE,4-(2-AMINOETHYL)-BENZENESULFONAMIDE HCL 4-(2-AMINOETHYL)BENZENESULFONAMIDE MONOHYDROCHLORIDE, 99+%,4-(2-Aminoethyl)-Benzenesulfonamide Hydrochloride N-ACETYL-4-(2-AMINOETHYL)-BENZENESULFONAMIDE 4-(2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)ETHYL)BENZENESULFONAMIDE Glisamuride 4-amino-N-(2-aminoethyl)benzenesulfonamide N-(2-aminoethyl)benzenesulfonamide 4-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfamide glisoxepide Glicetanile N-(2-AMINOETHYL)BENZENESULFONAMIDE HYDROCHLORIDE 3-(1-AMINOETHYL)BENZENESULFONAMIDE HYDROCHLORIDE

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