ChemicalBook Product Catalog Analytical Chemistry Standard Standard Substance D-Ephedrine hydrochloride

D-Ephedrine hydrochloride

D-Ephedrine hydrochloride Basic information
Product Name:D-Ephedrine hydrochloride
Synonyms:2-MethylaMino-1-phenylpropan-2-ol;D-(+)-EPHEDRINE HYDROCHLORIDE;d-alpha-(1-methylaminoethyl)benzyl alcohol;D-ALPHA-(1-METHYLAMINOETHYL)BENZYL ALCOHOL HYDROCHLORIDE;alpha-(1-(methylamino)ethyl)-,hydrochloride,(s-(r*,s*))-benzenemethano;alpha-[1-(methylamino)ethyl]-,hydrochloride,[s-(theta,s)]-benzenemethano;(1S,2R)-(+)-EPHEDRINE HYDROCHLORIDE;(1S,2R)-(+)-ALPHA-(1-METHYLAMINOETHYL)BENZYL ALCOHOL HYDROCHLORIDE
CAS:24221-86-1
MF:C10H16ClNO
MW:201.69
EINECS:246-090-7
Product Categories:Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical Raw Materials
Mol File:24221-86-1.mol
D-Ephedrine hydrochloride Structure
D-Ephedrine hydrochloride Chemical Properties
Melting point 218-220 °C(lit.)
alpha 34.3 º (c=5, H2O)
Fp 9℃
storage temp. Refrigerator
solubility DMF: 10 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 5 mg/ml
form A crystalline solid
optical activity[α]23/D +34.3°, c = 5 in H2O
BRN 6118541
CAS DataBase Reference24221-86-1(CAS DataBase Reference)
EPA Substance Registry SystemBenzenemethanol, .alpha.-[(1R)-1-(methylamino)ethyl]-, hydrochloride, (.alpha.S)- (24221-86-1)
Safety Information
Hazard Codes Xn,T,F
Risk Statements 22-39/23/24/25-23/24/25-11
Safety Statements 22-25-45-36/37-16-7
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 3
RTECS KB1925000
HS Code 29394100
MSDS Information
ProviderLanguage
(1S,2R)-(+)-Ephedrine hydrochloride English
SigmaAldrich English
D-Ephedrine hydrochloride Usage And Synthesis
Chemical Propertieswhite crystalline powder
Usesα- and β-Adrenergic agonist. Bronchodilator.
Safety ProfileA poison by intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also EPHEDRINE
Purification MethodsRecrystallise the hydrochloride from EtOH/Et2O. The free base crystallises from *C6H6 with m 40-41o (Skita et al. Chem Ber 66 974 1933]. [Beilstein 13 H 254, 13 II 375, 13 III 1721, 13 IV 1879.]
D-Ephedrine hydrochloride Preparation Products And Raw materials
(R)-A,A-BIS(4-PHENOXYPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE (R)-A,A-BIS(3,5-DICHLOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE (R)-A,A-BIS(3-CHLOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE DL-Ephedrine hydrochloride (R)-A,A-BIS(4-THIOANISOLE)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE 8-chlororugulovasine A (R)-A,A-BIS(3,4,5-TRIFLUOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE Topotecan hydrochloride NOSCAPINE HYDROCHLORIDE (R)-A,A-BIS(3,5-DIFLUOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE (R)-A,A-BIS(3-FLUOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE D-Ephedrine hydrochloride (4R,5R)-(-)-2,2-DIMETHYL-A,A,A',A'-TETRA(1-NAPHTHYL)-1,3-DIOXOLANE-4,5-DIMETHANOLATOTITANIUM(IV) DICHLORIDE ACETONITRILE ADDUCT (-)-BICUCULLINE METHOCHLORIDE (-)-Pseudoephedrine chloramphenicol glucuronide (R)-A,A-BIS(3,4-DIFLUOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE NOSCAPINE HYDROCHLORIDE HYDRATE
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