ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Aminopyrimidine 2-Aminopyrimidine-5-boronic Acid Pinacol Ester

2-Aminopyrimidine-5-boronic Acid Pinacol Ester

2-Aminopyrimidine-5-boronic Acid Pinacol Ester Basic information
Product Name:2-Aminopyrimidine-5-boronic Acid Pinacol Ester
Synonyms:2-AMINO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIMIDINE;2-AMINOPYRIMIDINE-5-BORONIC ACID, PINACOL ESTER;5-METHOXYTHIOPHENE-2-BORONIC ACID;5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine;2-PyriMidinaMine,5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;2-Aminopyrimidine-5-boronic acid pinacol ester 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine;5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine;5-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)pyrimidin-2-ylamine, 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrimidin-2-ylamine, 2-aminopyrimidine-5-boronic acid pinacol ester, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-ylamine, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-ylamine, 2‐aminopyrimidine‐5‐boronic acid, pinacol ester, 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
CAS:402960-38-7
MF:C10H16BN3O2
MW:221.06
EINECS:
Product Categories:Heterocyclic Compounds;Amino;Organoborons;Pyrimidine
Mol File:402960-38-7.mol
2-Aminopyrimidine-5-boronic Acid Pinacol Ester Structure
2-Aminopyrimidine-5-boronic Acid Pinacol Ester Chemical Properties
Melting point 209-211°C
Boiling point 394.8±34.0 °C(Predicted)
density 1.13±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly, Heated)
pka3.66±0.10(Predicted)
form solid
color white to off-white
Water Solubility Slightly soluble in water. Soluble in chloroform.
InChIKeyBPQVMIDUTRJYSC-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi,Xn,T
Risk Statements 36/37/38-22-25
Safety Statements 26-36/37/39-36/39-45
RIDADR UN 2811 6.1 / PGIII
TSCA No
HazardClass IRRITANT
HS Code 2933599590
MSDS Information
2-Aminopyrimidine-5-boronic Acid Pinacol Ester Usage And Synthesis
Chemical PropertiesLight Beige Solid
Uses2-Aminopyrimidine-5-boronic Acid Pinacol Ester is used in the preparation of phosphoinositide-3-kinases (PI3K) inhibitors.
2-Aminopyrimidine-5-boronic Acid Pinacol Ester Preparation Products And Raw materials
Preparation Products2-(TERT-BUTOXYCARBONYLAMINO)PYRIMIDINE-5-BORONIC ACID, PINACOL ESTER-->(S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one-->Cyclobutanecarbonitrile, 1-[6-(2-amino-5-pyrimidinyl)-3-pyridinyl]-
2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 1-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-PIPERIDINE-4-CARBOXYLIC ACID 4-BENZYLOXY-2-DIMETHYLAMINO-PYRIMIDINE-5-BORONIC ACID 2-DIMETHYLAMINO-PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-(PIPERIDIN-1-YL)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-(4-METHYLPIPERAZIN-1-YL)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-AMINO-4-TRIFLUOROPYRIMIDINE-5-BORONIC ACID PINACOL ESTER [2-(1H-INDOL-3-YL)-ETHYL]-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-AMINE 2-(4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-PIPERAZIN-1-YL)-ETHANOL CYCLOPROPYL-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-AMINE 2-(PYRROLIDIN-1-YL)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-TERT-BUTYLOXYCARBONYLAMINO-4-HYDROXY-6-METHYL PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-Aminopyrimidine-5-boronic Acid Pinacol Ester 2-AMINOPYRIMIDINE-5-BORONIC ACID, PINACOL ESTER[MFCD06795685] 2-(TERT-BUTOXYCARBONYLAMINO)PYRIMIDINE-5-BORONIC ACID, PINACOL ESTER 4-Benzyloxy-2-piperidine-1-yl-pyrimidine-5-boronic acid pinacol ester 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 1-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-1H-PYRROLE-2-CARBALDEHYDE
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