ChemicalBook Product Catalog Chemical Reagents Organic reagents Imide (R)-(+)-1-Phenylethylamine

(R)-(+)-1-Phenylethylamine

(R)-(+)-1-Phenylethylamine Basic information
Product Name:(R)-(+)-1-Phenylethylamine
Synonyms:(1R)-1-PHENYLETHANAMINE;(1R)-1-PHENYLETHYLAMINE;(+)-D-ALPHA-METHYLBENZYLAMINE;D(+)-ALPHA-METHYLBENZYLAMINE;D-ALPHA-METHYLBENZYLAMINE;D-(+)-ALPHA-PHENYLETHYLAMINE;D-ALPHA-PHENYLETHYLAMINE;D-(+)-A-METHYLBENZYLAMINE
CAS:3886-69-9
MF:C8H11N
MW:121.18
EINECS:223-423-4
Product Categories:Amines;Aromatics;chiral;Amines (Chiral);Analytical Chemistry;Chiral Reagents;Asymmetric Synthesis;Chiral Building Blocks;e.e. / Absolute Configuration Determination (NMR);Enantiomer Excess & Absolute Configuration Determination;for Resolution of Acids;Optical Resolution;Synthetic Organic Chemistry;Chiral Compound;Benzene derivatives;3886-69-9
Mol File:3886-69-9.mol
(R)-(+)-1-Phenylethylamine Structure
(R)-(+)-1-Phenylethylamine Chemical Properties
Melting point -10 °C
alpha 40 º (neat)
Boiling point 187-189 °C(lit.)
density 0.952 g/mL at 20 °C(lit.)
vapor pressure 0.5 mm Hg ( 20 °C)
refractive index n20/D 1.526(lit.)
Fp 175 °F
storage temp. 2-8°C
solubility 40g/l
pka9.04±0.10(Predicted)
form Liquid
color Clear colorless
PH>7 (40g/l, H2O, 20℃)
optical activity[α]23/D +38°, neat
Water Solubility 40 g/L (20 ºC)
Sensitive Air Sensitive
Merck 14,6026
BRN 2410916
InChIKeyRQEUFEKYXDPUSK-SSDOTTSWSA-N
LogP1.31-1.49 at 25℃
CAS DataBase Reference3886-69-9(CAS DataBase Reference)
NIST Chemistry ReferenceBenzenemethanamine, «alpha»-methyl-, (R)-(3886-69-9)
EPA Substance Registry SystemBenzenemethanamine, .alpha.-methyl-, (.alpha.R)- (3886-69-9)
Safety Information
Hazard Codes C
Risk Statements 21/22-34
Safety Statements 26-28-36/37/39-45-28A-27
RIDADR UN 2735 8/PG 2
WGK Germany 3
F 3-10-23-34
Autoignition Temperature355 °C DIN 51794
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29214980
MSDS Information
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(R)-(+)-1-Phenylethylamine English
ACROS English
SigmaAldrich English
ALFA English
(R)-(+)-1-Phenylethylamine Usage And Synthesis
Chemical PropertiesColorless to light yellow liqui
Uses(R)-(+)-1-Phenylethylamine is a chiral amine used for the determination of the enantiomeric purity of acids.
Uses(R)-(+)-a-Methylbenzylamine also known as (R)-(+)-1-Phenylethylamine may be used in resolution of a chiral arylalkylamine involving high-conversion enantioselective condensation with capric acid followed by hydrolysis to yield corresponding (R)-(+)-amide.
DefinitionChEBI: The (R)-enantiomer of 1-phenylethanamine.
General Description(R)-(+)-α-Methylbenzylamine is a chiral amine.
Flammability and ExplosibilityNonflammable
Purification MethodsDissolve the amine in toluene, dry over NaOH and distil; fraction boiling at 187-188o/atm is collected. Store it under N2 to avoid forming the carbamate and urea. Similarly for the S-(-) enantiomer [2627-86-3]. [Ingersoll Org Synth Coll Vol II 503 1943, Robinson & Snyder Org Synth Coll Vol III 717 1955, Beilstein 12 IV 2424, 2425.]
(R)-(+)-1-Phenylethylamine Preparation Products And Raw materials
Preparation Products(S)-3-Aminoquinuclidine dihydrochloride-->(R)-(+)-2-Methyl-2-propanesulfinamide-->(R)-(+)-1,1'-Bi-2-naphthol-->(S)-(-)-1,1'-Bi-2-naphthol-->(R)-(+)-BORNYLAMINE-->(R,R)-(+)-BIS(ALPHA-METHYLBENZYL)AMINE HYDROCHLORIDE-->(+)-Bis[(R)-1-phenylethyl]amine-->DL-alpha-Methylbenzylamine-->(R)-PIPERAZINE-2-CARBOXYLIC ACID-->(R)-(+)-(3,4-Dimethoxy)benzyl-1-phenylethylamine-->(S)2-(2-Oxo pyrrolidin-1-yl)-Butiric acid methyl ester-->(R)-(+)-N-(1-PHENYLETHYL)PHTHALAMIC ACID-->(R)-(+)-N,ALPHA-DIMETHYLBENZYLAMINE-->(R)-(+)-N-Benzyl-1-phenylethylamine-->(METHYLTHIO)ACETIC ACID-->N-(2-Benzoyl-4-chlorophenyl)-2-{[(1R)-1-phenylethyl]amino}acetamide-->1-[(1R)-1-Phenylethyl]pyrrolidin-2-one
(R,R)-(+)-N,N'-BIS(ALPHA-METHYLBENZYL)SULFAMIDE (R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE TRITYL ISOTHIOCYANATE 5,5-DIPHENYL-2-THIOHYDANTOIN 5,5-Diphenylhydantoin N-(TRIPHENYLMETHYL)ANILINE (-)-1-[5-CHLORO-2-(METHYLAMINO)PHENYL]-1,2,3,4-TETRAHYDROISOQUINOLINE,(-)-TARTRATE (+)-Bicuculline Trityl azide D-TUBOCURARINE CHLORIDE Aminodiphenylmethane hydrochloride TRT-GLY-OH Benzhydrylamine 9H-FLUOREN-9-AMINE Levamisole hydrochloride 2,2-Diphenylglycine (R)-(-)-1-(1-NAPHTHYL)ETHYL ISOCYANATE TRIPHENYLMETHYLAMINE
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