ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Phenylalanine derivatives N-Cbz-L-Phenylalanine

N-Cbz-L-Phenylalanine

N-Cbz-L-Phenylalanine Basic information
Product Name:N-Cbz-L-Phenylalanine
Synonyms:N-benzyloxycarbonyl-L-3-phenylalanine;N-CBZ-L-PHENYLALANINE CRYSTALLINE;CBZ-L-PHENYLALAINE;n-benzyloxycarbonyl-1-phenylalanine;N-Carbobenzyloxy-L-phenylalanine, 99+%;CBZ-L-PHENYLALANINE-OH;CBZ-L-Phe-OH;BOC-PHE (N-BENZYLOXYCARBONYL)-L-PHENYLALANINE
CAS:1161-13-3
MF:C17H17NO4
MW:299.32
EINECS:214-599-3
Product Categories:Phenylalanine [Phe, F];Z-Amino Acids and Derivatives;Amino Acids;Amino Acids (N-Protected);Biochemistry;Cbz-Amino Acids;Protected Amino Acids;AMINOACIDS DERIVATIVES;Amino Acid Derivatives;PROTECTED AMINO ACID & PEPTIDES;Chiral Compounds;Cbz-Amino acid series
Mol File:1161-13-3.mol
N-Cbz-L-Phenylalanine Structure
N-Cbz-L-Phenylalanine Chemical Properties
Melting point 85-87 °C(lit.)
alpha 5 º (c=5,acetic acid)
Boiling point 440.65°C (rough estimate)
density 1.1441 (rough estimate)
refractive index 5.3 ° (C=4, AcOH)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMF (Sparingly), DMSO (Slightly), Methanol (Slightly)
pka3.86±0.10(Predicted)
form Powder
color White to off-white
optical activity[α]20/D +5°, c = 5 in acetic acid
BRN 2222826
CAS DataBase Reference1161-13-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 62-36/37/38-20/21/22
Safety Statements 22-24/25-36-26
WGK Germany 3
RTECS AY4343000
HS Code 29242990
MSDS Information
ProviderLanguage
Z-Phe-OH English
SigmaAldrich English
ACROS English
ALFA English
N-Cbz-L-Phenylalanine Usage And Synthesis
Chemical Propertieswhite amorphous powder
UsesN-Cbz-L-Phenylalanine is used in the synthesis of neurokinin antagonists. Furthermore it is used in the preparation of Co(II), Zn(II), and Cd(II) complexes with N-benzyloxycarbonyl-S-phen ylalanine that displays antimicrobial activity against common strains of bacteria.
UsesInhibitor of thermolysin
UsesN-(Carbobenzyloxy)-L-phenylalanine is used in the synthesis of neurokinin antagonists. Furthermore it is used in the preparation of Co(II), Zn(II), and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine that displays antimicrobial activity against common strains of bacteria.
Biochem/physiol ActionsInhibitor of thermolysin
N-Cbz-L-Phenylalanine Preparation Products And Raw materials
Raw materialsN-CARBOBENZYLOXY-D-PHENYLALANINE, 99+%-->Z-PHE-OBZL-->Z-PHE-OME-->(S)-Cbz-Phenylalaninol-->Benzyl chloroformate-->L-Phenylalanine
Preparation ProductsSemax-->N-Propyl L-Z-PhenylalaninaMide
CBZ-L-PHENYLALANINE HYDROXYSUCCINIMIDE ESTER,N-ALPHA-CBZ-L-PHENYLALANINE N-HYDROXYSUCCINIMIDE ESTER,CBZ-L-PHENYLALANINE N-SUCCINIMIDE ESTER Z-PHE-OBZL Phenprobamate N-Benzyloxycarbonyl-O-tert-butyl-L-tyrosine dicyclohexylamine salt Z-TYR-OH L-Phenylalanine Z-TYR(BZL)-OH Z-TYR(TBU)-OH BOC-PHE-OH Z-2-NAL-OH N-Cbz-L-Phenylalanine Z-TYR(BZL)-OSU Z-TYR(Z)-OH Fmoc-Phe-OH Z-TYR-OHEX Z-TYR-ONP Z-TYR-OME D-Phenylalanine
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