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| | N-Carbethoxyphthalimide Basic information |
| Product Name: | N-Carbethoxyphthalimide | | Synonyms: | 1,3-dihydro-1,3-dioxo-2h-isoindole-2-carboxylicaciethylester;1,3-dioxo-2-isoindolinecarboxylicaciethylester;N-(Carboethoxy)phthalimide~Nefkens;Ethyl phthalimidocarboxylate;N-Ethoxycarbonylphthalimide [for Peptide synthesis];N-Carbethoxyphthalimide, 98+%;N-Carbethoxyphthalimide, 99+%;2H-Isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester | | CAS: | 22509-74-6 | | MF: | C11H9NO4 | | MW: | 219.19 | | EINECS: | 245-048-5 | | Product Categories: | Biochemistry;N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Phthalimides;Peptide Synthesis;Protection & Derivatization Reagents (for Synthesis);Protective Reagents (Peptide Synthesis);Synthetic Organic Chemistry | | Mol File: | 22509-74-6.mol |  |
| | N-Carbethoxyphthalimide Chemical Properties |
| Melting point | 90-92 °C(lit.) | | Boiling point | 360°C (rough estimate) | | density | 1.3219 (rough estimate) | | vapor pressure | 0.003-0.006Pa at 20-25℃ | | refractive index | 1.4950 (estimate) | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | -3.02±0.20(Predicted) | | form | Crystalline Powder | | color | White | | Water Solubility | insoluble | | BRN | 196340 | | InChIKey | VRHAQNTWKSVEEC-UHFFFAOYSA-N | | LogP | 1.1 at 20℃ and pH6.6-6.9 | | CAS DataBase Reference | 22509-74-6(CAS DataBase Reference) | | NIST Chemistry Reference | 2H-isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester(22509-74-6) | | EPA Substance Registry System | 2H-Isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester (22509-74-6) |
| | N-Carbethoxyphthalimide Usage And Synthesis |
| Chemical Properties | White crystalline powder | | Uses | N-Carbethoxyphthalimide is used in the synthetic preparation of a novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors. | | Purification Methods | Crystallise the imide from toluene/pet ether (or *benzene/pet ether). It is partly soluble in Et2O, *benzene and CHCl3. [Heller & Jacobsohn Chem Ber 54 1112 1921, Beilstein 21/10 V 428.] |
| | N-Carbethoxyphthalimide Preparation Products And Raw materials |
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