2,6-Difluorobenzamide

2,6-Difluorobenzamide Basic information

Product Name:	2,6-Difluorobenzamide
Synonyms:	2,6-Difluorobenzamide97%;2,6-Difluorbenzamid;2,6-Difluorobenzoylamide;2,6-DIFLUOROBENZAMIDE, 98+%;Fluorine benzaMide 2, 6-2;2,6-difluoro-benzamid;2,6-DIFLUOROBENZAMIDE;2，6-difluorobenzaminde
CAS:	18063-03-1
MF:	C7H5F2NO
MW:	157.12
EINECS:	241-972-8
Product Categories:	Amides;Carbonyl Compounds;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Organic Building Blocks;intermediate;Aryl Fluorinated Building Blocks;Building Blocks;C7;Carbonyl Compounds;Chemical Synthesis;Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;18063-03-1
Mol File:	18063-03-1.mol

2,6-Difluorobenzamide Chemical Properties

Melting point	145-148 °C (lit.)
Boiling point	51-52C/15Tor
density	1,199g/cm
refractive index	1,508
storage temp.	Sealed in dry,Room Temperature
solubility	ethanol: soluble5%, clear to turbid, colorless to light yellow
pka	14.54±0.50(Predicted)
form	Solid
color	Off-White
BRN	2047480
InChIKey	AVRQBXVUUXHRMY-UHFFFAOYSA-N
LogP	0.011-0.25 at 25℃
CAS DataBase Reference	18063-03-1(CAS DataBase Reference)
NIST Chemistry Reference	Benzamide, 2,6-difluoro-(18063-03-1)
EPA Substance Registry System	Benzamide, 2,6-difluoro- (18063-03-1)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20
Safety Statements	26-37/39-36/37
WGK Germany	1
RTECS	CV4355050
HazardClass	IRRITANT
HS Code	29242990
Toxicity	rat,LC50,inhalation,> 2100mg/m3/4H (2100mg/m3),National Technical Information Service. Vol. OTS0543293,

MSDS Information

Provider	Language
2,6-Difluorobenzamide	English
SigmaAldrich	English
ACROS	English
ALFA	English

2,6-Difluorobenzamide Usage And Synthesis

Description	2,6-Difluorobenzamide is a major metabolite of pesticide diflubenzuron and has been quantitated by HPLC/diode-array method.
Chemical Properties	white to yellowish powder
Uses	2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates. It is also used in the synthesis of pesticide intermediates, which can be used to produce various insecticides such as fluazuron, chlorpyrifos, and pyrethroids.
Preparation	2,6-Difluorobenzamide is obtained by hydrolysis of 2,6-difluorobenzonitrile.

2,6-Difluorobenzamide Preparation Products And Raw materials

Raw materials	Potassium fluoride-->2,6-Difluorobenzonitrile-->2,6-Difluorobenzoic acid
Preparation Products	Chlorfluazuron-->Hexaflumuron-->Flufenoxuron-->Teflubenzuron-->2,6-Difluoroaniline-->2,6-Difluorobenzoyl isocyanate-->Diflubenzuron-->4-Amino-2,6-difluorophenol-->2,6-Difluoro-4-nitrophenol

N-(3-amino-4-fluorophenyl)-2,6-difluorobenzamide N-(3-amino-4-methylphenyl)-3,5-difluorobenzamide N-(3-aminopropyl)-2,6-difluorobenzamide N-(3-amino-4-fluorophenyl)-3,5-difluorobenzamide 2,6-DIFLUORO-N-(4-[(4-METHYLPHENYL)SULFONYL]PHENYL)BENZENECARBOXAMIDE 2,6-Difluorobenzoyl hydrazine N-(4-[(4-BROMOPHENYL)SULFANYL]PHENYL)-2,6-DIFLUOROBENZENECARBOXAMIDE N-(3-amino-4-fluorophenyl)-2,4-difluorobenzamide N-(3-bromophenyl)-2,6-difluorobenzamide 2,6-DIFLUORO-3-NITROBENZAMIDE N-PENTAFLUOROBENZOYLIMIDAZOLE 2,6-DIFLUORO-N-(4-[(4-METHYLPHENYL)SULFANYL]PHENYL)BENZENECARBOXAMIDE 2,4,6-TRIFLUOROBENZAMIDE N-(2-aminophenyl)-2,6-difluorobenzamide N-(3-acetylphenyl)-2,6-difluorobenzamide N-(3-amino-2,6-dimethylphenyl)-3,5-difluorobenzamide N-(3-amino-2-methylphenyl)-2,5-difluorobenzamide 4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE

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