DEHYDRO ARIPIPRAZOLE

DEHYDRO ARIPIPRAZOLE Basic information
Product Name:DEHYDRO ARIPIPRAZOLE
Synonyms:DEHYDRO ARIPIPRAZOLE;7-[4-[4-(2,3-Dichlorophenyl)-1-Piperazinyl]Butoxy]-2(1H)-Quinolinone;2(1H)-Quinolinone,7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-;7-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)quinolin-2(1H)-one;Aripiprazole Related CoMpound G;Aripiprazole USP impurity G(EP impurity E);Dehydro aripiprazole solution;Aripiprazole Related Compound G (25 mg) (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}quinolin-2(1H)-one)
CAS:129722-25-4
MF:C23H25Cl2N3O2
MW:446.37
EINECS:
Product Categories:
Mol File:129722-25-4.mol
DEHYDRO ARIPIPRAZOLE Structure
DEHYDRO ARIPIPRAZOLE Chemical Properties
Melting point >139oC (dec.)
Boiling point 654.4±55.0 °C(Predicted)
density 1.281±0.06 g/cm3(Predicted)
Fp 349℃
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly, Heated)
pka11.22±0.70(Predicted)
form Solid
color White to Off-White
InChIKeyCDONPRYEWWPREK-UHFFFAOYSA-N
Safety Information
Hazard Codes F,T
Risk Statements 11-23/24/25-39/23/24/25-52/53
Safety Statements 16-36/37-45-61
RIDADR UN 3286 8(6.1)(3) / PGII
WGK Germany 1
HS Code 2933790002
MSDS Information
DEHYDRO ARIPIPRAZOLE Usage And Synthesis
UsesDehydro Aripiprazole (Aripiprazole EP Impurity E; Aripiprazole USP Related Compound G) is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.
General DescriptionDehydro Aripiprazole is the primary, active metabolite of aripiprazole, marketed as the atypical antipsychotic Abilify? for the treatment of schizophrenia, bipolar disorder, and clinical depression. This new certified solution standard is suitable for use in LC or GC applications including forensic or clinical toxicology analysis and urine drug testing.
DEHYDRO ARIPIPRAZOLE Preparation Products And Raw materials
Raw materialsAripiprazole-->1-(2,3-Dichlorophenyl)-piperazine-->7-Hydroxyquinolinone-->7-(4-BROMOBUTOXY)-QUINOLINE-2(1H)-ONE
Amoxicillin Diketopiperazine (Mixture of Diastereomers) (4S)-2-[[[(2R)-2-AMino-2-(4-hydroxyphenyl)acetyl]aMino]Methyl]-5,5-diMethyl-4-thiazolidinecarboxylic Acid (Mixture of DiastereoMers) 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone Alfuzosin L-Amoxicillin 2-Deschloro Aripiprazole 1-(2,3-Dichlorophenyl)piperazine hydrochloride 7-METHOXY-1H-QUINOLIN-2-ONE 1-(2-Chlorophenyl)piperazine hydrochloride DEHYDRO ARIPIPRAZOLE 7-Hydroxyquinolinone DEHYDROARIPIPRAZOLE, HYDROCHLORIDE 1-(4-PHENOXYBUTYL)PIPERAZINE Aripiprazole N1,N1-DIMETHYL-2,3-DICHLOROANILINE 1-(4-HYDROXYBUTYL)-4-METHYLPIPERAZINE 4-PROPOXYACETANILINE DEHYDRO ARIPIPRAZOLE-D8, HYDROCHLORIDE

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