CARBOXYIBUPROFEN

CARBOXYIBUPROFEN Basic information
Product Name:CARBOXYIBUPROFEN
Synonyms:2-[4-(2-Methyl-3-hydroxy-3-oxopropyl)phenyl]propionic acid;Ibuprofen Carboxylic Acid;3-[4-(1-Carboxyethyl)phenyl]-2-methylpropionic acid;CARBOXYIBUPROFEN;IBUPROFEN CARBOXYLIC ACID (MIXTURE OF DIASTERIOMERS);CARBOXYIBUPROFEN (MIXTURE OF STEREOISOMERS);2,4(2-Carboxypropyl)phenylpropionic Acid;2-[4-(2-Carboxypropyl)phenyl]propionic Acid
CAS:15935-54-3
MF:C13H16O4
MW:236.26
EINECS:
Product Categories:Metabolite Reference Standard;Chiral Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:15935-54-3.mol
CARBOXYIBUPROFEN Structure
CARBOXYIBUPROFEN Chemical Properties
Melting point 114-116°C
Boiling point 416.2±25.0 °C(Predicted)
density 1.211±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka4.39±0.10(Predicted)
color White to Off-White
Safety Information
MSDS Information
CARBOXYIBUPROFEN Usage And Synthesis
DescriptionIbuprofen carboxylic acid is a major metabolite of ibuprofen (Item Nos. 70280 | 16793 | 16794). It prevents fructose-, cyanate-, and prednisolone-induced inactivation of catalase and fructose- and cyanate-induced inactivation of fumarase when used at a concentration of 2 mM and penetrates into the lens of isolated bovine eyes. Ibuprofen carboxylic acid has been found in bank filtrate and surface water, as well as influent and effluent wastewater, and is considered a micropollutant.
Chemical PropertiesWhite Solid
UsesThe major metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes.
DefinitionChEBI: A dicarboxylic acid that is ibuprofen in which one of the methyl groups in the isobutyl portion has been converted to the corresponding carboxylic acid.
CARBOXYIBUPROFEN Preparation Products And Raw materials
Carboxy styrene-butadiene latex Ibuprofen Isopropyl Ester CYCLAZOSIN HYDROCHLORIDE 1-Oxo Ibuprofen Ibuprofen Ethyl Ester 1,3-bis(4-isobutylphenyl)butan-1-one 2-(4-Methylphenyl)propanoic acid Ibuprofen Ester Impurity 2-(4-isobutylphenyl)propionaldehyde Ibuprofen Impurity 4 ISOCARBOXAZID (200 MG) Propyphenazone Silica MagBeads (-COOH) Diethyl 2-[4-(2,2-Dicarboethoxypropyl)phenyl]-2-methyl Malonate 2-[4-(1,1-Dicarboethoxy)benzyl]-2-methyl Malonic Acid Ibuprofen CARBOXYIBUPROFEN 3-[4-(2-HYDROXY-ETHYL)-PHENYL]-PROPAN-1-OL

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