Polydatin

Polydatin Basic information
Product Name:Polydatin
Synonyms:RESVERATROL GLUCOSIDE;RESVERATROL-3-B-D-GLUCOSIDE;RESVERATROL 3-BETA-MONO-D-GLUCOSIDE;TRANS-RESVERATROL 3-O-BETA-D-GLUCURONIDE;TRANS-RESVERATROL-O-BETA-GLUCOSIDE;3-Hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl-beta-D-glucopyranoside;3-HYDROXY-5-(2-(4-HYDROXYPHENYL)ETHENYL)PHENYL-BETA-D-GLUCOSIDE;3, 5, 4'-trihydroxystilbene 3-glucoside
CAS:27208-80-6
MF:C20H22O8
MW:390.39
EINECS:
Product Categories:chemical reagent;pharmaceutical intermediate;Nutritional Ingredients;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Anthocyanins;The group of Polydatin;Aromatics;Glucuronides;Heterocycles
Mol File:27208-80-6.mol
Polydatin Structure
Polydatin Chemical Properties
Melting point 223-226 °C(lit.)
alpha -77.5 º (c=0.2, EtOH)
Boiling point 707.7±60.0 °C(Predicted)
density 1.521±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility DMSO, Ethanol, Methanol
pka9.21±0.10(Predicted)
form Solid
color Off-White
λmax305nm(EtOH)(lit.)
LogP0.412 (est)
CAS DataBase Reference27208-80-6(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 29389090
MSDS Information
ProviderLanguage
SigmaAldrich English
Polydatin Usage And Synthesis
DescriptionPolydatin is a stilbene glucoside and a precursor to trans-resveratrol (Item No. 70675) that has been found in V. vinifera and has diverse biological activities. It scavenges DPPH radicals and inhibits copper-induced lipid peroxidation (IC50s = 198 and 19.1 μM, respectively). Polydatin inhibits the proliferation of, and induces cell cycle arrest at the S phase in, Caco-2 colon cancer cells. It decreases infarct size, cardiomyocyte fibrosis, and apoptosis in a mouse model of myocardial ischemia-reperfusion injury induced by left anterior descending (LAD) coronary artery occlusion when administered at a dose of 40 mg/kg per day.
Chemical PropertiesOff-White Solid
UsesA Stilbenoid glucoside and is a major Resveratrol derivative.
Usesantioxidant
DefinitionChEBI: A stilbenoid that is trans-resveratrol substituted at position 3 by a beta-D-glucosyl residue.
General DescriptionThis substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Polydatin Preparation Products And Raw materials
DanshenP.E Aloe emodin Piceid(polydatin) Oxyresveratrol Neosperidin dihydrochalcone RHAPONTIN Polydatin PHENYL VALERATE Ascorbyl glucoside ASTRINGIN Resveratrol 2,3,5,4'-TETRAHEDROXYSTILBENE-3-O-D-GLUCOSIDE 3,5-DIHYDROXY-4'-METHOXYSTILBENE 3-O-BETA-D-GLUCOSIDE Polydatin PHENYL-BETA-D-GLUCOPYRANOSIDE CHLOROPHOSPHONAZO III Phenylhydrazine ISORHAPHONTIN

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