ChemicalBook Product Catalog Chemical Reagents Silane reagent BIS(O-TRIMETHYLSILYL)THYMINE

BIS(O-TRIMETHYLSILYL)THYMINE

BIS(O-TRIMETHYLSILYL)THYMINE Basic information
Product Name:BIS(O-TRIMETHYLSILYL)THYMINE
Synonyms:O,O'-Bis(trimethylsilyl)thymine 97%;BIS(O-TRIMETHYLSILYL)THYMINE;0,0-Bis (trimethylsilyl)thymine;2,4-Bis(trimethylsiloxy)-5-methylpyrimidine;trimethyl-(5-methyl-2-trimethylsilyloxypyrimidin-4-yl)oxysilane;2,4-Bis(trimethylsilyl)-5-methyluracil;2,4-Bis-O-(trimethylsilyl)thymine;2,4-Bis[(trimethylsilyl)oxy]-5-methylpyrimidine
CAS:7288-28-0
MF:C11H22N2O2Si2
MW:270.48
EINECS:
Product Categories:Building Blocks;Heterocyclic Building Blocks;Pyrimidines
Mol File:7288-28-0.mol
BIS(O-TRIMETHYLSILYL)THYMINE Structure
BIS(O-TRIMETHYLSILYL)THYMINE Chemical Properties
Melting point 73-75 °C(lit.)
Boiling point 127-130 °C18 mm Hg(lit.)
density 0.974±0.06 g/cm3(Predicted)
form solid
pka1.50±0.29(Predicted)
Hydrolytic Sensitivity7: reacts slowly with moisture/water
EPA Substance Registry SystemPyrimidine, 5-methyl-2,4-bis[(trimethylsilyl)oxy]- (7288-28-0)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
TSCA No
MSDS Information
ProviderLanguage
SigmaAldrich English
BIS(O-TRIMETHYLSILYL)THYMINE Usage And Synthesis
Chemical PropertiesColourless solid, very sensitive to moisture
UsesO,O′-Bis(trimethylsilyl)thymine is a reactive intermediate for the preparation of nucleosides.
BIS(O-TRIMETHYLSILYL)THYMINE Preparation Products And Raw materials
Preparation Products5-Methyluridine-->1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione-->THYMINE-BETA-D-ARABINOFURANOSIDE
2,4-BIS-TRIMETHYLSILANYLOXY-PYRIMIDINE 5-METHYLPYRIMIDIN-4-OL BIS(O-TRIMETHYLSILYL)THYMINE 2-Hydroxy-5-methylpyrimidine Uracil Thymine
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