Rivaroxaban Impurity 27

Rivaroxaban Impurity 27 Basic information
Product Name:Rivaroxaban Impurity 27
Synonyms:Rivaroxaban Impurity 13/2-[(2S)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione;Rivaroxaban Impurity 27;2-[(2S)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione;1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-;(S)-2-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione? (Rivaroxaban Impurity)
CAS:1369969-44-7
MF:C21H21N3O5
MW:395.41
EINECS:
Product Categories:
Mol File:1369969-44-7.mol
Rivaroxaban Impurity 27 Structure
Rivaroxaban Impurity 27 Chemical Properties
Boiling point 734.9±60.0 °C(Predicted)
density 1.421±0.06 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka13.91±0.20(Predicted)
color White to Off-White
Safety Information
MSDS Information
Rivaroxaban Impurity 27 Usage And Synthesis
Uses2-[(2S)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione is an intermediate in the synthesis of ent-Rivaroxaban (R538005), the R-isomer of Rivaroxaban (R538000), which is a novel antithrombotic agent.
Rivaroxaban Impurity 27 Preparation Products And Raw materials
2-Chloro-6-methylaniline 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- 2-Chlorothiophene 2-Thiophenecarboxylic acid 3-Morpholinone, 4-phenyl- (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione 5-Methyl-2-thiophenecarboxylic acid Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- Rivaroxaban iMpurity 5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE Rivaroxaban Related Compound (R-4-(4-(5-(Aminomethyl)-2-Oxooxazolidin-3-yl)phenyl-Morpholin-3-One HCl) (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl (S)-(+)-GLYCIDYL PHTHALIMIDE Rivaroxaban Impurity 93 2-Chloro-5-thiophenecarboxaldehyde 4-(2-nitrophenyl)Morpholin-3-one 4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID 2,5-DICHLOROTHIOPHENE-3-CARBOXYLIC ACID

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