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Febuxostat Bromo Impurity

Febuxostat Bromo Impurity Basic information
Product Name:Febuxostat Bromo Impurity
Synonyms:Febuxostat Bromo Impurity;2-(3-bromo-4-isobutoxyphenyl)-4- methylthiazole-5-carboxylic acid;3-Descyano 3-Bromo-febuxostat;Febuxostat-4;Febuxostat Impurity 12/Febuxostat Bromo Impurity/2-(3-bromo-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;2-(3-bromo-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid;2-(3-bromo-4-isobutoxyphenyl);5-Thiazolecarboxylic acid, 2-[3-bromo-4-(2-methylpropoxy)phenyl]-4-methyl-
CAS:144060-40-2
MF:C15H16BrNO3S
MW:370.26
EINECS:
Product Categories:
Mol File:144060-40-2.mol
Febuxostat Bromo Impurity Structure
Febuxostat Bromo Impurity Chemical Properties
Boiling point 510.9±60.0 °C(Predicted)
density 1.444±0.06 g/cm3(Predicted)
pka2.60±0.10(Predicted)
Safety Information
MSDS Information
Febuxostat Bromo Impurity Usage And Synthesis
Uses3-Descyano 3-Bromo-febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
Febuxostat Bromo Impurity Preparation Products And Raw materials
isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate FeBuxostat Impurity 26 Febuxostat Descyano Impurity FeBuxostat Impurity 33 Febuxostat impurity 37 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate FeBuxostat Impurity 18 ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5- carboxylate 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Impurity 14 2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid FeBuxostat Impurity 32 ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5- carboxylate 2-(4-HYDROXY-PHENYL)-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat impurity 36
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