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Febuxostat Impurity 14

Febuxostat Impurity 14 Basic information
Product Name:Febuxostat Impurity 14
Synonyms:2-(4-isobutoxy-3-isocyanophenyl)-4-methylthiazole;Febuxostat Impurity 58/Febuxostat Descarboxy Impurity/2-isobutoxy-5-(4-methylthiazol-2-yl)benzonitrile;Febuxostat-58;Febuxostat Descarboxy Impurity;Febuxostat Impurity K;Descarboxyl Febuxostat;Febuxostat Impurity 14;Febuxostat impurities 14
CAS:1335202-60-2
MF:C15H16N2OS
MW:272.37
EINECS:
Product Categories:
Mol File:1335202-60-2.mol
Febuxostat Impurity 14 Structure
Febuxostat Impurity 14 Chemical Properties
Melting point 84-86°C
Boiling point 435.5±55.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
pka2.48±0.10(Predicted)
form Solid
color Off-White to Pale Pink
Safety Information
MSDS Information
Febuxostat Impurity 14 Usage And Synthesis
UsesDescarboxyl Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout.
Febuxostat Impurity 14 Preparation Products And Raw materials
isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate FeBuxostat Impurity 26 Febuxostat Descyano Impurity FeBuxostat Impurity 33 Febuxostat impurity 37 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate FeBuxostat Impurity 18 ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5- carboxylate 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Febuxostat Bromo Impurity 2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid FeBuxostat Impurity 32 ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5- carboxylate 2-(4-HYDROXY-PHENYL)-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid
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