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Axitinib Sulfonyl

Axitinib Sulfonyl Basic information
Product Name:Axitinib Sulfonyl
Synonyms:Axitinib Impurity b;Axitinib Sulfone;Axitinib Sulfonyl Impurity;Axitinib D;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]-;N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide;Axitinib Impurity 6/Axitinib Sulfone/N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]-benzamide;Axitinib Sulfone Impurity
CAS:1348536-59-3
MF:C22H18N4O3S
MW:418.47
EINECS:
Product Categories:
Mol File:1348536-59-3.mol
Axitinib Sulfonyl Structure
Axitinib Sulfonyl Chemical Properties
Boiling point 735.3±60.0 °C(Predicted)
density 1.393±0.06 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka10.59±0.40(Predicted)
color Off-White to Pale Yellow
Safety Information
MSDS Information
Axitinib Sulfonyl Usage And Synthesis
UsesN-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide (Axitinib sulfone) is an impurity of axitinib (A794650), a tyrosine kinase inhibitor and is used in cancer therapy.
Axitinib Sulfonyl Preparation Products And Raw materials
2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide Axitinib Impurity 4 Axitinib Impurity a BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl- Axitinib Impurity 27 Axitinib Impurity 13 Axitinib Impurity 18 Axitinib Impurity d Axitinib Impurity 10 Axitinib Impurity 26 Axitinib Impurity 23 Axitinib N-Glucuronide (M7) Axitinib Impurity 3 Axitinib Impurity 14 Axitinib Impurity 19 Axitinib Impurity 11 Axitinib Impurity 28 Axitinib Impurity 24
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