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| | 6-Hydroxycoumarin Basic information |
| | 6-Hydroxycoumarin Chemical Properties |
| Melting point | 249-253 °C (lit.) | | Boiling point | 248.82°C (rough estimate) | | density | 1.2500 | | refractive index | 1.5380 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | pka | 8.92±0.20(Predicted) | | λmax | 349nm(EtOH)(lit.) | | LogP | 0.650 (est) | | CAS DataBase Reference | 6093-68-1(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29322010 |
| | 6-Hydroxycoumarin Usage And Synthesis |
| Description | 6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity. | | Occurrence | 6-Hydroxycoumarin is a natural product found in Grevillea robusta and Amburana cearensis with data available. | | Uses | 6-Hydroxycoumarin (cas# 6093-68-1) is a compound useful in organic synthesis. | | Preparation | (1) synthesis of 6-aminocoumarins：In polar solvent, using 6- nitroscumarin as raw material, using hydrazine hydrate as hydrogen Source, is reducing catalyst using ferric chloride (FeCl36H2O), at ambient pressure reduces 6-nitroscumarin, prepare 6- aminocoumarins；
(2) synthesis of 6-Hydroxycoumarins：In sulfuric acid solution, one-step method is by 6-aminocoumarins after diazo-reaction Direct hydrolysis, prepares 6-Hydroxycoumarins in high yield.
The preparation method of 6 Hydroxycoumarins |
| | 6-Hydroxycoumarin Preparation Products And Raw materials |
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