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| | Glyphosine Basic information |
| | Glyphosine Chemical Properties |
| Melting point | 263°C | | Boiling point | 668.4±65.0 °C(Predicted) | | density | 1.952±0.06 g/cm3(Predicted) | | storage temp. | +2C to +8C | | solubility | PBS (pH: 7.2):5.0(Max Conc. mg/mL);19.01(Max Conc. mM) | | pka | pK1 1.42; pK2 2.10; pK3 5.02; pK4 6.40; pK5 11.19(at 25℃) | | form | Solid | | color | White | | Water Solubility | 248g/L(20 ºC) | | Merck | 13,4526 | | BRN | 1884944 | | CAS DataBase Reference | 2439-99-8(CAS DataBase Reference) | | EPA Substance Registry System | Glyphosine (2439-99-8) |
| Hazard Codes | Xi | | Risk Statements | 41 | | Safety Statements | 26-2 | | RIDADR | UN 3261 8/PG 3 | | WGK Germany | 1 | | RTECS | MB9120000 | | HS Code | 2922.49.8000 | | Toxicity | LD50 orally in rats: 3925 mg/kg; dermally in rabbits: >5010 mg/kg (Ahlrichs) |
| | Glyphosine Usage And Synthesis |
| Uses | Chemical ripener; plant growth regulator. | | Uses | Application: Complexing agent; pK-values: pK1: ·2, pK2: 2.0, pK3: 5.20, pK4: 6.77, pK5: 10.89
Anti-diabetic; delay onset of diabetes in non-obese NOD mice
Glyphosine binds to a pocket of MHC class II molecules I-Ag7 and DQ8, and modify T cell responses to the autoantigenic insulin B chain fragment 9–23 (B:9–23) peptide. Glyphosine stimulate IL-10 production and delay onset of diabetes in non-obese NOD mice. | | Definition | ChEBI: A tertiary amino compound that consists of glycine bearing two N-phosphonomethyl substituents. | | General Description | N,N-Bis(phosphonomethyl)glycine was present in the ligand bound to human apotransferrin. | | Biochem/physiol Actions | Anti-diabetic; delay onset of diabetes in non-obese NOD mice |
| | Glyphosine Preparation Products And Raw materials |
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