GMBS

GMBS Basic information
Product Name:GMBS
Synonyms:1H-Pyrrole-2,5-dione, 1-[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]-;4-MaleiMidobutyric acid N-hydroxysucciniMide ester(GMBS);3-MaleiMidobutyric acid N-hydroxysucciniMide ester;CIVENTICHEM CV-2656;GAMMA-MALEIMIDOBUTYRIC ACID N-HYDROXYSUCCINIMIDE ESTER;GMBS;GMBS Crosslinker;N-Succinimidyl 4-Maleimidobutyrate 
CAS:80307-12-6
MF:C12H12N2O6
MW:280.23
EINECS:625-693-2
Product Categories:heteroXlink;Heterobifunctional Crosslinker;Maleimide Derivatives;N-Substituted Maleimides;N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Succinimides;Cross Linking Reagents;MTS & Sulfhydryl Active Reagents
Mol File:80307-12-6.mol
GMBS Structure
GMBS Chemical Properties
Melting point 123-129 °C
Boiling point 461.3±47.0 °C(Predicted)
density 1.49±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility chloroform: 100 mg/mL
form powder
pka-2.27±0.20(Predicted)
color White to Pale Yellow
BRN 6427689
Stability:Hygroscopic, Moisture Sensitive
InChIInChI=1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2
InChIKeyPVGATNRYUYNBHO-UHFFFAOYSA-N
SMILESN1(CCCC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
10-21
HS Code 29280000
MSDS Information
ProviderLanguage
SigmaAldrich English
GMBS Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA short, sulfhydryl and amino reactive heterobifunctional crosslinking reagent. Introduces maleimide groups into IgM
UsesA heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Useful in enzyme immunoassays
GMBS Preparation Products And Raw materials
4-Maleimidobutyric Acid-NHS(GMBS) N-Hydroxysuccinimide 4-ACETAMIDOBUTYRIC ACID N-METHOXY-N-METHYL-PROPIONAMIDE 2,5-dioxopyrrolidin-1-yl propanoate 4-FORMAMIDOBUTYRIC ACID SULFO-GMBS,SULPHO GMBS GMBS N-Acetoxysuccinimide N-Methoxy-N-methylacetamide 4-MALEIMIDOBUTYRIC ACID 5-(DIMETHYLAMINO)AMYLAMINE N,N,O-TRIACETYLHYDROXYLAMINE N-METHOXYDIACETAMIDE N-Butylmaleimide N-N-BUTYLACRYLAMIDE N-(4-MALEIMIDOBUTYRYLOXY)SULFOSUCCINIMIDE SODIUM SALT (SULFO-GMBS) N-PROPYLMALEIMIDE

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