McMMAE

McMMAE Basic information
Product Name:McMMAE
Synonyms:Mc MMAE;McMMAE;Mc-MMAE;37: PN: WO2007140371 PAGE: 273 claimed sequence;Maleimidocaproyl-monomethylauristatin E;L-Valinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-;Mc-MMAE,Inhibitor,Drug-Linker Conjugates for ADC,McMMAE,Microtubule/Tubulin,Mc MMAE,inhibit
CAS:863971-24-8
MF:C49H78N6O10
MW:911.18
EINECS:
Product Categories:ADCs;ADC LINKER
Mol File:863971-24-8.mol
McMMAE Structure
McMMAE Chemical Properties
Boiling point 1025.2±65.0 °C(Predicted)
density 1.144±0.06 g/cm3(Predicted)
storage temp. Store at -20°C,unstable in solution, ready to use.
solubility DMSO: ≥ 51 mg/mL (55.97 mM)
pka13.63±0.46(Predicted)
form Powder
Safety Information
MSDS Information
McMMAE Usage And Synthesis
McMMAE Preparation Products And Raw materials
Raw materialsMonoMethyl auristatin E-->6-Aminocaproic acid-->6-Maleimidocaproic acid
MonoMethyl Dolastatin 10 McMMAD MC-MMAF MonoMethylauristatin F VcMMAD

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