Oxamic acid sodium salt

Oxamic acid sodium salt Basic information
Product Name:Oxamic acid sodium salt
Synonyms:aminooxo-aceticacimonosodiumsalt;AMINOOXOACETIC ACID SODIUM SALT;OXALIC ACID MONOAMIDE SODIUM SALT;OXAMIC ACID SODIUM SALT;oxamic acid sodium;OxamicacidsodiumsaltOxamicacidsodiumsalt;Aminooxoacetic acid sodium salt, Oxalic acid monoamide sodium salt, Oxamic acid sodium salt;2-Amino-2-oxoacetic acid sodium salt
CAS:565-73-1
MF:C2H2NNaO3
MW:111.03
EINECS:209-290-5
Product Categories:
Mol File:565-73-1.mol
Oxamic acid sodium salt Structure
Oxamic acid sodium salt Chemical Properties
Melting point 300 °C
storage temp. Inert atmosphere,Room Temperature
solubility PBS (pH 7.2): 10 mg/ml
form solid
Water Solubility Soluble in water (10 mg/ml).
BRN 6538153
InChIInChI=1S/C2H3NO3.Na/c3-1(4)2(5)6;/h(H2,3,4)(H,5,6);/q;+1/p-1
InChIKeyRQVZIJIQDCGIKI-UHFFFAOYSA-M
SMILESC(=O)(N)C([O-])=O.[Na+]
CAS DataBase Reference565-73-1(CAS DataBase Reference)
EPA Substance Registry SystemSodium oxamate (565-73-1)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
10
TSCA Yes
HS Code 29241990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
Oxamic acid sodium salt Usage And Synthesis
Chemical Propertieswhite crystalline powder
UsesOxamic acid sodium salt is a lactate dehydrogenase (LDH) inhibitor. It is a suitable compound to investigate cancer cells that utilize the glycolytic pathway.This compound is suitable for lactate dehydrogenase (LDH) related research. It can be used as an inhibitor of gluconeogenesis useful for anticancer research.
ApplicationSodium oxamate, an inhibitor of LDH-C4, prevented the AR induced by lysophosphatidylcholine (LPC) or NADH. Oxamic acid sodium salt is an lactic acid dehydrogenase. Sperm suspension and cytosol fraction activities were inhibited by sodium oxamate. As cancer cells are often dependent on glycolysis for ATP production, sodium oxamate has implications as an anticancer compound.
Biochem/physiol ActionsSodium oxamate influences the fatty acid metabolism. It might be useful for the treatment of diabetes.
Oxamic acid sodium salt Preparation Products And Raw materials
Raw materialsEthanol-->Sodium hydroxide-->Ethyl acetate-->Tetrahydrofuran-->Toluene-->Ammonia-->Diethyl oxalate-->Ethyl oxalyl monochloride-->ETHYL OXAMATE
Potassium binoxalate Ferrous oxalate dihydrate Sodium phytate POTASSIUM TITANIUM OXALATE DIHYDRATE Stannous oxalate Ferric ammonium oxalate trihydrate EC 2.7.1.40 ETHYL OXAMATE Oxalic acid SODIUM GLYOXYLATE Oxamic acid sodium salt Oxamic acid

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