BRL 15572 HYDROCHLORIDE

BRL 15572 HYDROCHLORIDE Basic information
Product Name:BRL 15572 HYDROCHLORIDE
Synonyms:3-(4-(3-chlorophenyl)piperazin-1-yl)-1,1-diphenylpropan-2-ol dihydrochloride;BRL 15572 HYDROCHLORIDE;3-[4-(4-CHLOROPHENYL)PIPERAZIN-1-YL]-1,1-DIPHENYL-2-PROPANOL HCL;3-[4-(4-CHLOROPHENYL)PIPERAZIN-1-YL]-1,1-DIPHENYL-2-PROPANOL HYDROCHLORIDE;BRL15572HCl;BRL-15572 (dihydrochloride);4-(3-Chlorophenyl)-alpha-(diphenylmethyl)-1-piperazineethanol dihydrochloride;BRL-15572 dihydrochloride (BRL15572
CAS:193611-72-2
MF:C25H28Cl2N2O
MW:443.41
EINECS:
Product Categories:Inhibitors;Serotonin receptor
Mol File:193611-72-2.mol
BRL 15572 HYDROCHLORIDE Structure
BRL 15572 HYDROCHLORIDE Chemical Properties
storage temp. Inert atmosphere,2-8°C
solubility Soluble in DMSO
form Powder
Safety Information
MSDS Information
BRL 15572 HYDROCHLORIDE Usage And Synthesis
UsesBRL 15572 Hydrochloride is an analog of BRL 15572, which is a preferential antagonist at native human 5-HT1D receptors.
Biological ActivityA selective h5-HT 1D antagonist, displaying 60-fold selectivity over h5-HT 1B , and exhibiting little or no affinity for a range of other receptor types.
target5-HT1D
references[1] price g w, burton m j, collin l j, et al. sb-216641 and brl-15572–compounds to pharmacologically discriminate h5-ht1b and h5-ht1d receptors. naunyn-schmiedeberg's archives of pharmacology, 1997, 356(3): 312-320.
BRL 15572 HYDROCHLORIDE Preparation Products And Raw materials
Pyridine hydrochloride Aniline hydrochloride Betaine hydrochloride Dimethylamine hydrochloride Methylamine hydrochloride Trimethylamine hydrochloride 4-(3-CHLOROPHENYL)-ALPHA-(DIPHENYLMETHYL)-1-PIPERAZINEETHANOL HYDROCHLORIDE 1,1-DIPHENYL-2-PROPANOL BRL 15572 HYDROCHLORIDE 1-(3-PHENYLPROPYL)PIPERAZINE

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