ChemicalBook Product Catalog Biochemical Engineering Inhibitors PI3K / Akt / mTOR mTOR inhibitors PaloMid 529 (P529)

PaloMid 529 (P529)

PaloMid 529 (P529) Basic information
Product Name:PaloMid 529 (P529)
Synonyms:PaloMid 529 (P529);PaloMid 529;P529;8-(1-Hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]-6H-dibenzo[b,d]pyran-6-one;8-(1-Hydroxyethyl)-2-Methoxy-3-((4-Methoxybenzyl)oxy)-6H-benzo[c]chroMen-6-one;3-(4-methoxybenzyloxy)-8-(1-hydroxyethyl)-2-methoxy-6H-benzo[c]chromen-6-one;8-(1-Hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]-6H-dibenzo[b,d]pyran-6-one Palomid 529 (P529) SG 00529;SG 00529
CAS:914913-88-5
MF:C24H22O6
MW:406.43
EINECS:806-313-6
Product Categories:Inhibitors;API
Mol File:914913-88-5.mol
PaloMid 529 (P529) Structure
PaloMid 529 (P529) Chemical Properties
Boiling point 614.0±55.0 °C(Predicted)
density 1.280
storage temp. -20°C
solubility DMSO: soluble10mg/mL, clear
form powder
pka11.79±0.20(Predicted)
color white to beige
Safety Information
Hazard Codes Xn
Risk Statements 22
RIDADR UN 2811 6.1 / PGIII
WGK Germany 3
RTECS HP8756500
HS Code 29322090
MSDS Information
PaloMid 529 (P529) Usage And Synthesis
UsesPalomid 529 is a novel non-steroidal small molecule inhibitor
Biological ActivityPalomid 529 (P529) inhibits the mTORC1 and mTORC2 complexes and reduces the phosphorylation of pAktS473, pGSK3βS9 and pS6, but has no effect on pMAPK and pAktT308. Phase 1.
targetmTORC1
PaloMid 529 (P529) Preparation Products And Raw materials
BEZ235 (NVP-BEZ235, Dactolisib) 7-hydroxy-4-Methyl-2-oxo-2H-1-Benzopyran-8-carboxaldehyde DAPT OSI-027 4-PIPERIDINOL, PROPIONATE, HYDROCHLORIDE Saracatinib MK-2206 2HCl Propylamine
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