(S)-(-)-Tolvaptan

(S)-(-)-Tolvaptan Basic information
Product Name:(S)-(-)-Tolvaptan
Synonyms:(S)-(-)-Tolvaptan;Tolvaptan (S)-Isomer;N-[4-[(5S)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide;Tolvaptan Impurity S-Isomer;Benzamide, N-[4-[[(5S)-7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl-
CAS:331947-44-5
MF:C26H25ClN2O3
MW:448.94
EINECS:
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:331947-44-5.mol
(S)-(-)-Tolvaptan Structure
(S)-(-)-Tolvaptan Chemical Properties
Melting point 157-164°C
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
Safety Information
MSDS Information
(S)-(-)-Tolvaptan Usage And Synthesis
UsesAn enantiomer of Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist irrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
UsesAn enantiomer of Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
(S)-(-)-Tolvaptan Preparation Products And Raw materials
(R)-(+)-Tolvaptan N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide

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