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2-Carboxybenzoyl Amlodipine

2-Carboxybenzoyl Amlodipine Basic information
Product Name:2-Carboxybenzoyl Amlodipine
Synonyms:Amlodipine EP Impurity I;2-(2-((4-(2-Chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2;2-Carboxybenzoyl Amlodipine;2-[[2-[[(4RS)-4-(2-Chlorophenyl)-3-(ethoxycarbonyl)- 5-(Methoxycarbonyl)-6-Methyl-1,4-dihydropyridin-2-yl] Methoxy]ethyl]-carbaMoyl]benzoic Acid;2-[[2-[(2-Carboxybenzoyl)aMino]ethoxy]Methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-Methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester;2-(2-((4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(Methoxycarbonyl)-6-Methyl-1,4-dihydropyridin-2-yl)Methoxy)ethylcarbaMoyl)benzoic acid;AMlodipine IMpurity H (EP);AMlodipine EP IMpurity H
CAS:318465-73-5
MF:C28H29ClN2O8
MW:556.99
EINECS:608-671-7
Product Categories:Aromatics;Heterocycles;Intermediates;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:318465-73-5.mol
2-Carboxybenzoyl Amlodipine Structure
2-Carboxybenzoyl Amlodipine Chemical Properties
Melting point 160-162°C
Boiling point 727.6±60.0 °C(Predicted)
density 1.305±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka3.49±0.36(Predicted)
form Solid
color White to Off-White
PH4.94 at 27.1℃ and 1000g/L
LogP23 at 25℃
Safety Information
MSDS Information
2-Carboxybenzoyl Amlodipine Usage And Synthesis
UsesAmlodipine Besilate (A633500) impurity. Used in the process for preparing Amlodipine benzenesulfonate. Amlodipine EP Impurity H
UsesAs Amlodipine Besilate (A633500) impurity, 2-Carboxybenzoyl AMlodipine can be used in the process for preparing Amlodipine benzenesulfonate.
2-Carboxybenzoyl Amlodipine Preparation Products And Raw materials
Amlodipine iMpurity K Amlodipine Dimethyl Ester Dehydro AMlodipine Oxalate N-[2-[(Methylamino)carbonyl]benzoyl] Bis(aminoethoxy) Amlodipine Desmethyl amolodipine (S)-AMlodipine-d4 AMlodipine IMpurity F Maleate diethyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)Methyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate Amlodipine Impurity 13 3,5-Pyridinedicarboxylicacid, 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester Amlodipine Impurity 25 Amlodipine Impurity 48 d-Amlodipine Amlodipine Impurity 10 Amlodipine N-Galactose Amlodipine Impurity 32 Amlodipine Impurity 50
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