1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid

1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid Basic information
Product Name:1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid
Synonyms:1-(4-FLUOROPHENYLCARBAMOYL)CYCLOPROPANECARBOXYLIC ACID;Cyclopropanecarboxylic acid, 1-[[(4-fluorophenyl)aMino]carbonyl]-;1-{[(4-fluorophenyl)aMino]carbonyl}cyclopropanecarboxylic acid;InterMediate of Cabozantinib;FLUOROPHENYLCARBAMOYL)CYCLOPROPANECARBOXYLIC ACID;((4-fluorophenyl)carbamoyl)cyclopropane carboxylic acid;1-(5-FLUOROPHENYLCARBAMOYL)CYCLOPROPANECARBOXYLIC ACID;1-(4-FLUOROPHENYLCARBAMOYL)CYCLOPROPANECARBOXYLIC ACID(849217-48-7)
CAS:849217-48-7
MF:C11H10FNO3
MW:223.2
EINECS:1592732-453-0
Product Categories:849217-48-7
Mol File:849217-48-7.mol
1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid Structure
1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid Chemical Properties
Melting point 173.0 to 177.0 °C
Boiling point 475.2±30.0 °C(Predicted)
density 1.521
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
pka3.48±0.20(Predicted)
color White to Almost white
InChIInChI=1S/C11H10FNO3/c12-7-1-3-8(4-2-7)13-9(14)11(5-6-11)10(15)16/h1-4H,5-6H2,(H,13,14)(H,15,16)
InChIKeyPFMAFXYUHZDKPY-UHFFFAOYSA-N
SMILESC1(C(NC2=CC=C(F)C=C2)=O)(C(O)=O)CC1
Safety Information
HS Code 2924.29.9500
MSDS Information
1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid Usage And Synthesis
Chemical PropertiesWhite powdery substance.
Uses1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid is a useful research chemical that can be used as a cabozantinib intermediate.
Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]- Cabozantinib impurity 1DYH 1,1-Cyclopropanedicarboxamide, N,N'-bis[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]- Cabozantinib Malate Cyclopropanecarboxylic acid, 1-[(phenylaMino)carbonyl]- Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- 1,1-Cyclopropanedicarboxamide,N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-phenyl- Cyclopropanecarboxylic acid, 1-[[[4-[[7-methoxy-6-(sulfooxy)-4-quinolinyl]oxy]phenyl]amino]carbonyl]- 2-Aminocyclohexanone 5-aminotetrazole 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Cabozantinib impurity DX2 Cabozantinib Impurity EXA 4-Benzothiazolamine (9CI) 4-chloro-6,7-dimethoxyquinoline N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide 4-Aminodiphenylamine Cabozantinib Impurity 5

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