2-AMINO-5-FLUOROACETOPHENONE

2-AMINO-5-FLUOROACETOPHENONE Basic information

Product Name:	2-AMINO-5-FLUOROACETOPHENONE
Synonyms:	1-(2-amino-5-fluorophenyl)ethan-1-one;1-(2-Amino-5-fluorophenyl);2-AMINO-5-FLUOROACETOPHENONE;1-(2-AMino-5-fluorophenyl)ethanone;Ethanone, 1-(2-amino-5-fluorophenyl)-;5-Fluoro-2-Amino-Acetophenone
CAS:	2343-25-1
MF:	C8H8FNO
MW:	153.15
EINECS:
Product Categories:
Mol File:	2343-25-1.mol

2-AMINO-5-FLUOROACETOPHENONE Chemical Properties

Melting point	64-65 °C
Boiling point	264.2±20.0 °C(Predicted)
density	1.201±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	2.37±0.10(Predicted)

Safety Information

HS Code

2914790090

MSDS Information

2-AMINO-5-FLUOROACETOPHENONE Usage And Synthesis

Uses	1-(2-Amino-5-fluorophenyl)ethanone is a useful research chemical.
Uses	2-Amino-5-fluoroacetophenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
Synthesis	600 g of 2-ethynyl-4-fluoroaniline and 4 L of water were added to the reaction flask, and then 476 g of hydrochloric acid (concentration: 35%) was added, and thereaction was carried out at 50 ??C for 36 hours.After the reaction, the temperature is lowered to 20-25 ??C, the reaction solution is adjusted to pH 8-9 with 50% sodium hydroxide solution, thetemperature is controlled to not exceed 30 ??C during pH adjustment, and the filter cake is washed with 1 L of water and decompressed at 50 ??C. After drying for 12 h, 622 g of pale yellow solid was obtained, yield91.4%.HPLC purity was 99.2%.

2-AMINO-5-FLUOROACETOPHENONE Preparation Products And Raw materials

Raw materials

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