Isoderrone

Isoderrone Basic information
Product Name:Isoderrone
Synonyms:3-(2,2-Dimethyl-2H-1-benzopyran-6-yl)-5,7-dihydroxy-4H-1-benzopyran-4-one;Isoderrone;4H-1-Benzopyran-4-one, 3-(2,2-dimethyl-2H-1-benzopyran-6-yl)-5,7-dihydroxy-;5,7-dihydroxy-2',2'-dimethyl-2'H,4H-[3,6'-bichromen]-4-one
CAS:121747-89-5
MF:C20H16O5
MW:336.34
EINECS:
Product Categories:
Mol File:121747-89-5.mol
Isoderrone Structure
Isoderrone Chemical Properties
Boiling point 562.1±50.0 °C(Predicted)
density 1.368±0.06 g/cm3(Predicted)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form cryst.
pka6.49±0.20(Predicted)
color Yellow
Safety Information
MSDS Information
Isoderrone Usage And Synthesis
DescriptionIsoderrone is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 27 ± 7 uM, suggests that it may be a new drug for treatment of type 2 diabetes. Isoderrone shows inhibitory effects on α-glucosidase in vitro.
DefinitionChEBI: Isoderrone is a hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 5 and 7 and a 6,6-dimethyl-3,6-dihydro-2H-pyran across positions 3' and 4' respectively. It has been isolated from Ficus mucuso. It has a role as a plant metabolite. It is functionally related to an isoflavone.
targetTyrosinase
Isoderrone Preparation Products And Raw materials
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Hydroxyecdysone (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Artemether beta-Sitosterol hydroxygenkwanin alpha-Terpineol beta-Eudesmol MOSLOFLAVONE alpha-Cyperone

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