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BEPRIDIL

BEPRIDIL Basic information
Product Name:BEPRIDIL
Synonyms:1-pyrrolidineethanamine,beta-((2-methylpropoxy)methyl)-n-phenyl-n-(phenylmethy;BEPRIDIL;Bepadin;CERM-1978;Vascor;Bepridil hydrochloride monohydrate/bepridil;1-[2-(N-Benzylanilino)-1-(isobutoxymethyl)ethyl]pyrrolidine;ORG-5730
CAS:64706-54-3
MF:C24H34N2O
MW:366.54
EINECS:
Product Categories:Active Pharmaceutical Ingredients
Mol File:64706-54-3.mol
BEPRIDIL Structure
BEPRIDIL Chemical Properties
Boiling point bp0.1 184°; bp0.5 192°
density 1.0392 (rough estimate)
refractive index nD20 1.5538
storage temp. 2-8°C
pka9.21±0.20(Predicted)
Water Solubility 7.43g/L(37 ºC)
Safety Information
MSDS Information
BEPRIDIL Usage And Synthesis
UsesBepridil is protective against Ebola virus. Bepridil is used in biological study of shortening of electromechnical window in ketamine/xylazine-anesthetized guinea pig model improved QTc interval prolongation and assessed pro-arrhythmic risk during early drug development. Bepridil is also used in therapeutic use in novel high/low solubility classification methods for new molecular entities.
DefinitionChEBI: A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
Enzyme inhibitorThis substituted pyrrolidine (FWfree-base = 366.55 g/mol) is a calcium channel blocker that inhibits the Na+ /Ca2+ exchange, exhibiting antiarrhythmic, antianginal, and vasodilatory properties. Bepridil inhibits the growth of certain brain tumors in vitro. Bepridil also binds to troponin C. Target(s): Ca2+ channels; ATP-sensitive K+ channels; Na+ -activated K+ channels.
Benzydamine hydrochloride Molsidomine Nicardipine Trazodone Lercanidipine Cisapride Esmolol hydrochloride Bepridil, HCl N-Benzyl-2-(1-pyrrolidinyl)ethanamine BEPRIDIL HYDROCHLORIDE MONOHYDRATE BEPRIDIL BEPRIDIL HYDROCHLORIDE N-BENZYL-2-(1-PYRROLIDINYL)-1-PROPANAMINE Bepridil hydrochloride N-Phenylbenzylamine histapyrrodine
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