5-Fluoro-1,3-isobenzofurandione

5-Fluoro-1,3-isobenzofurandione Basic information
Product Name:5-Fluoro-1,3-isobenzofurandione
Synonyms:5-fluoro-3-isobenzofurandione;5-Fluoro-isobenzofuran-1,3-dione;5-FLUORO-BENZO[C]FURAN-1,3-DIONE;5-Fluoro-1,3-isobenzofurandione;5-FLUORO-2-BENZOFURAN-1,3-DIONE;4-FLUOROPHTHALIC ACID ANHYDRIDE;4-FLUOROBENZENE-1,2-DICARBOXYLIC ANHYDRIDE;4-Fluorophthalic
CAS:319-03-9
MF:C8H3FO3
MW:166.11
EINECS:1312995-182-4
Product Categories:Heterocycles;Carbonyl Compounds;Carboxylic Acid Anhydrides;Organic Building Blocks;Phthalic Acids, Esters and Derivatives;API intermediates
Mol File:319-03-9.mol
5-Fluoro-1,3-isobenzofurandione Structure
5-Fluoro-1,3-isobenzofurandione Chemical Properties
Melting point 75-79 °C (lit.)
Boiling point 148°C 20mm
density 1.55
Fp >93°C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Soluble in sodium hydroxide.
form powder to crystal
color White to Almost white
Sensitive Moisture Sensitive
BRN 131281
InChIKeyXVMKZAAFVWXIII-UHFFFAOYSA-N
CAS DataBase Reference319-03-9(CAS DataBase Reference)
EPA Substance Registry System1,3-Isobenzofurandione, 5-fluoro- (319-03-9)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38-42/43
Safety Statements 26-36/37/39-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 2
Hazard Note Irritant
TSCA Yes
HazardClass IRRITANT, MOISTURE SENSITIVE
PackingGroup 
HS Code 29173990
MSDS Information
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5-Fluoro-1,3-isobenzofurandione English
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5-Fluoro-1,3-isobenzofurandione Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses4-Fluorophthalic anhydride is used in the preparation of 5-fluoro-2-pyridin-3-ylmethyl-isoindole-1,3-dione by reacting with C-pyridin-3-yl-methylamine.
Uses4-Fluorophthalic anhydride can be used as a reactant to prepare:
  • 4-amino substituted phthalimides applicable as potential fluorescent probes and fluorescent bioactive compounds.
  • 4,4′-bis(4-fluorophthalimido)diphenyl ether monomer, which is used in the synthesis of cardo polymers via nucleophilic substitution polymerization reaction.
  • Asymmetric polyimides by a solution polycondensation reaction.

General Description4-Fluorophthalic anhydride is a fluorinated building block commonly used in chemical synthesis for the preparation of polyimide, pesticides, herbicides, and fungicides. It can be synthesized by treating 4-chlorophthalic anhydride with potassium fluoride.
5-Fluoro-1,3-isobenzofurandione Preparation Products And Raw materials
Preparation Products6-Fluoro-3H-isobenzofuran-1-one
Phthalic acid Phthalic anhydride 3-Nitrophthalic anhydride AKOS 92364 4-Fluorophthalic acid 4,5-DIFLUOROPHTHALIC ANHYDRIDE 3,6-DIFLUOROPHTHALIC ANHYDRIDE 4-Fluoro-1,3-isobenzofurandione Biphenyl-4,4'-dicarboxylic acid AKOS 92366 5-Fluoro-1,3-isobenzofurandione 4-Fluoro-1,1'-biphenyl Tetrafluorophthalic anhydride

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